Регенеративные методы лечения травмы спинного мозга. Обзор литературы. Часть 4
https://doi.org/10.17650/1683-3295-2020-22-1-83-92
Аннотация
Проблема лечения травматических повреждений спинного мозга – одна из наиболее сложных и актуальных для современной медицины. В подавляющем большинстве случаев травма спинного мозга (ТСМ) приводит к стойкой инвалидизации пациентов, что имеет как медико-социальные, так и экономические последствия для пациента, его семьи и государства. Современные методы лечения ТСМ обладают крайне ограниченной эффективностью и не позволяют в достаточной степени восстановить утраченные функции центральной нервной системы. Регенеративные методы и, в частности, клеточная терапия – очень многообещающее направление, дающее надежду на эффективное лечение ТСМ. В обзоре освещены проблемы эпидемиологии и патогенеза ТСМ, описаны существующие методы терапии, а также перспективные методы регенеративной терапии. Особое внимание уделено результатам доклинических и клинических исследований в области клеточной терапии. Обзор разделен на 4 части. В 4-й части обсуждается применение клеток пуповинной крови человека при ТСМ, в частности рассмотрены преимущества данного вида терапии, описан состав клеточной смеси пуповинной крови, а также освещены результаты доклинических и клинических исследований.
Ключевые слова
Об авторах
В. А. Смирнов
ГБУЗ «Научно-исследовательский институт скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы»
Россия
129090 Москва, Большая Сухаревская пл., 3
Россия
129090 Москва, Большая Сухаревская пл., 3
А. А. Гринь
ГБУЗ «Научно-исследовательский институт скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы»; ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А. И. Евдокимова» Минздрава России
Россия
Россия
129090 Москва, Большая Сухаревская пл., 3; 127473 Москва, ул. Делегатская, 20, стр. 1
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Рецензия
Для цитирования:
Смирнов В.А., Гринь А.А. Регенеративные методы лечения травмы спинного мозга. Обзор литературы. Часть 4. Нейрохирургия. 2020;22(1):83-92. https://doi.org/10.17650/1683-3295-2020-22-1-83-92
For citation:
Smirnov V.A., Grin A.A. Regenerative treatment of spinal cord injury. Literature review. Part 4. Russian journal of neurosurgery. 2020;22(1):83-92. (In Russ.) https://doi.org/10.17650/1683-3295-2020-22-1-83-92
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