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Surgical complications after endoscopic transnasal transsphenoid removal of pituitary adenomas

Abstract

Objective: to analyze the literature data concerning various types of surgical complications after transnasal transsphenoid operations. Material and methods: The analysis of 38 trials published from 1997 till 2015 and reflected various complications after transnasal transsphenoid surgery of pituitary adenomas is conducted. The published papers contain data concerning postoperative period in patients (from 50 patients in case of single center experience to 5527 patients in multi-center analysis) during multi-year follow-up. Results: Nowadays the endoscopic surgery of pituitary adenomas is the treatment of choice. However the surgical treatment of chiasmosellar mass lesions may be accompanied by various complications, among them nasal liquorrhea, secondary meningitis and hemorrhage within the tumor bed are the most frequently observed. The injury of cavernous part of internal carotid artery is rare but more dreadful complication. Such delayed postoperative complications as sinusitis, synechiae of nasal cavity or nasal septum perforation are considered as separate group. Conclusions: Despite the relatively high amount of postoperative complications after transnasal removal of pituitary adenomas, the most of them are successfully responded to treatment. The literature data justify that the number of intraoperative and postoperative complications is consequently decreased under increasing the number of conducted operations.

About the Authors

E. V. Gormolysova
ФГБУ Федеральный центр нейрохирургии
Russian Federation


D. A. Rzaev
ФГБУ Федеральный центр нейрохирургии
Russian Federation


E. V. Galushko
ФГБУ Федеральный центр нейрохирургии
Russian Federation


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For citations:


Gormolysova E.V., Rzaev D.A., Galushko E.V. Surgical complications after endoscopic transnasal transsphenoid removal of pituitary adenomas. Russian journal of neurosurgery. 2017;(1):93-98. (In Russ.)

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