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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/1683-3295-2017-0-1-93-98</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-422</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>ХИРУРГИЧЕСКИЕ ОСЛОЖНЕНИЯ ПОСЛЕ ЭНДОСКОПИЧЕСКОГО ТРАНСНАЗАЛЬНОГО ТРАНССФЕНОИДАЛЬНОГО УДАЛЕНИЯ АДЕНОМ ГИПОФИЗА</article-title><trans-title-group xml:lang="en"><trans-title>Surgical complications after endoscopic transnasal transsphenoid removal of pituitary adenomas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гормолысова</surname><given-names>Екатерина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Gormolysova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">e_gormolysova@neuronsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рзаев</surname><given-names>Джамиль Афетович</given-names></name><name name-style="western" xml:lang="en"><surname>Rzaev</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">d_rzaev@neuronsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галушко</surname><given-names>Евгениий Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Galushko</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">e_galushko@neuronsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ Федеральный центр нейрохирургии</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>11</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>93</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гормолысова Е.В., Рзаев Д.А., Галушко Е.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Гормолысова Е.В., Рзаев Д.А., Галушко Е.В.</copyright-holder><copyright-holder xml:lang="en">Gormolysova E.V., Rzaev D.A., Galushko E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/422">https://www.therjn.com/jour/article/view/422</self-uri><abstract><p>Цель: анализ данных литературы, в которых указаны разные виды хирургических осложнений трансназальных транссфеноидальных операций. Материалы: В статье проведен анализ 38 исследований, опубликованных с 1997 г. по 2015 г., в которых отражены осложнения трансназальной транссфеноидальной хирургии аденом гипофиза. В источниках приведены данные течения послеоперационного периода многолетних наблюдений (от 50 при моноцентровом исследовании до 5527 человек при многоцентровом анализе). Результаты: В настоящее время эндоскопическое удаление аденом гипофиза является методом выбора у пациентов, которым показано хирургическое лечение. Тем не менее, хирургическое лечение образований хиазмально-селлярной области может сопровождаться рядом возможных осложнений. К наиболее частым осложнениям относят назоликворею, вторичный менингит, кровоизлияние в ложе удаленной опухоли. Среди редких, но более грозных осложнений выделяют повреждение кавернозного отдела внутренней сонной артерии. Как отдельная группа рассмотрены отдаленные послеоперационные осложнения, такие как синусит, развитие синехий полости носа или перфорации носовой перегородки. Выводы: Несмотря на достаточно высокую частоту осложнений после трансназального удаления аденом гипофиза, большинство нарушений успешно поддается лечению. Данные литературы свидетельствуют о том, что при увеличении количества проведенных вмешательств частота как интраоперационных, так и послеоперационных осложнений снижается.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to analyze the literature data concerning various types of surgical complications after transnasal transsphenoid operations. Material and methods: The analysis of 38 trials published from 1997 till 2015 and reflected various complications after transnasal transsphenoid surgery of pituitary adenomas is conducted. The published papers contain data concerning postoperative period in patients (from 50 patients in case of single center experience to 5527 patients in multi-center analysis) during multi-year follow-up. Results: Nowadays the endoscopic surgery of pituitary adenomas is the treatment of choice. However the surgical treatment of chiasmosellar mass lesions may be accompanied by various complications, among them nasal liquorrhea, secondary meningitis and hemorrhage within the tumor bed are the most frequently observed. The injury of cavernous part of internal carotid artery is rare but more dreadful complication. Such delayed postoperative complications as sinusitis, synechiae of nasal cavity or nasal septum perforation are considered as separate group. Conclusions: Despite the relatively high amount of postoperative complications after transnasal removal of pituitary adenomas, the most of them are successfully responded to treatment. The literature data justify that the number of intraoperative and postoperative complications is consequently decreased under increasing the number of conducted operations.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аденомы гипофиза</kwd><kwd>эндоскопическая трансназальная хирургия</kwd><kwd>осложнения</kwd><kwd>pituitary adenoma</kwd><kwd>endoscopic transnasal surgery</kwd><kwd>complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kadashev B.A., eds. Pituitary adenomas: clinical symptoms, diagnostics, treatment. Moscow 2007. Russian (Аденомы гипофиза: клиника, диагностика, лечение. Под ред. проф. Кадашева Б.А. М.: Издательство Триада, 2007).</mixed-citation><mixed-citation xml:lang="en">Kadashev B.A., eds. Pituitary adenomas: clinical symptoms, diagnostics, treatment. Moscow 2007. Russian (Аденомы гипофиза: клиника, диагностика, лечение. Под ред. проф. 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