Local fibrinolysis of hypertensive putaminal hematomas using Fortelyzin
V. G. Dashyan,
A. S. Nikitin,
R. Yu. Kryachev,
S. Ya. Zapesotskaya,
A. M. Semenov,
S. S. Markin,
O. V. Levchenko https://doi.org/10.63769/1683-3295-2025-27-3-134-142
Abstract
The first results of surgical treatment of patients with hypertensive putaminal hematomas using puncture aspiration and local fibrinolysis with Russian medication Fortelyzin are presented. Efficacy of this mediation is demonstrated. In patients with intracerebral hematomas of volume between 40 and 55 cm3, 87.5 to 100 % of hematoma volume were evacuated in 36-72 h. Further studies for determination of optimal dose and fibrinolysis scheme are necessary.
About the Authors
V. G. Dashyan
Russian University of Medicine, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Dolgorukovskaya St., Moscow 127006
A. S. Nikitin
Russian University of Medicine, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Dolgorukovskaya St., Moscow 127006
R. Yu. Kryachev
Russian University of Medicine, Ministry of Health of Russia
Russian Federation
Russian Federation
Roman Yu. Kryachev.
4 Dolgorukovskaya St., Moscow 127006
S. Ya. Zapesotskaya
Russian University of Medicine, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Dolgorukovskaya St., Moscow 127006
A. M. Semenov
Supragen LLC
Russian Federation
Russian Federation
Bld. 1, 6 Luzhnetskaya Naberezhnaya St., Moscow 119270
S. S. Markin
Supragen LLC
Russian Federation
Russian Federation
Bld. 1, 6 Luzhnetskaya Naberezhnaya St., Moscow 119270
O. V. Levchenko
Russian University of Medicine, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Dolgorukovskaya St., Moscow 127006
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Review
For citations:
Dashyan V.G., Nikitin A.S., Kryachev R.Yu., Zapesotskaya S.Ya., Semenov A.M., Markin S.S., Levchenko O.V. Local fibrinolysis of hypertensive putaminal hematomas using Fortelyzin. Russian journal of neurosurgery. 2025;27(3):134-142. (In Russ.) https://doi.org/10.63769/1683-3295-2025-27-3-134-142
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