Putiatary adenoma in a patient with neurofibromatosis type 2 (clinical observation and literature review)
https://doi.org/10.17650/1683-3295-2024-26-4-75-80
Abstract
Combination of pituitary adenomas with meningiomas or vestibular schwannomas is a rare occurrence: in scientific literature, only individual cases or small case series are described. The article presents a rare clinical observation of a female patient who underwent surgery and radiotherapy due to hormonally inactive pituitary adenoma and neurofibromatosis type 2 (intracranial meningioma and neurinoma (schwannoma)) found during a follow-up exam. A combination of histologically different intracranial tumors (pituitary adenoma, meningioma, and neurinoma) is extremely rare and requires corresponding approaches to treatment.
Keywords
pituitary adenoma,
neurinoma,
schwannoma,
neurofibromatosis type 2,
mutation,
multiple primary intracranial tumors
Supporting agencies: The work was performed without external funding
About the Authors
A. N. Shkarubo
N. N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
125047; 16 4th Tverskaya-Yamskaya St.; Moscow
Yu. Yu. Trunin
N. N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
125047; 16 4th Tverskaya-Yamskaya St.; Moscow
I. V. Chernov
N. N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
Ilya Valeryevich Chernov
125047; 16 4th Tverskaya-Yamskaya St.; Moscow
P. L. Kalinin
N. N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
125047; 16 4th Tverskaya-Yamskaya St.; Moscow
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Review
For citations:
Shkarubo A.N., Trunin Yu.Yu., Chernov I.V., Kalinin P.L. Putiatary adenoma in a patient with neurofibromatosis type 2 (clinical observation and literature review). Russian journal of neurosurgery. 2024;26(4):75-80. (In Russ.) https://doi.org/10.17650/1683-3295-2024-26-4-75-80
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