neurosurgeryНейрохирургияRussian journal of neurosurgery1683-32952587-7569Издательский дом "МедИНК"10.17650/1683-3295-2024-26-4-75-80neurosurgery-1612Research ArticleНАБЛЮДЕНИЕ ИЗ ПРАКТИКИFROM PRACTICEАденома гипофиза у пациента с нейрофиброматозом 2-го типа (клиническое наблюдение и обзор литературы)Putiatary adenoma in a patient with neurofibromatosis type 2 (clinical observation and literature review)https://orcid.org/0000-0003-3445-3115ШкарубоА. Н.ShkaruboA. N.

125047; ул. 4-я Тверская-Ямская, 16; Москва

125047; 16 4th Tverskaya-Yamskaya St.; Moscow

https://orcid.org/0000-0002-4240-5036ТрунинЮ. Ю.TruninYu. Yu.

125047; ул. 4-я Тверская-Ямская, 16; Москва

125047; 16 4th Tverskaya-Yamskaya St.; Moscow

https://orcid.org/0000-0002-9789-3452ЧерновИ. В.ChernovI. V.

Илья Валерьевич Чернов

125047; ул. 4-я Тверская-Ямская, 16; Москва

Ilya Valeryevich Chernov

125047; 16 4th Tverskaya-Yamskaya St.; Moscow

ichernov@nsi.ruhttps://orcid.org/0000-0001-9333-9473КалининП. Л.KalininP. L.

125047; ул. 4-я Тверская-Ямская, 16; Москва

125047; 16 4th Tverskaya-Yamskaya St.; Moscow

ФГАУ «Национальный медицинский исследовательский центр нейрохирургии им. акад. Н. Н. Бурденко» Минздрава РоссииРоссияN. N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of RussiaRussian Federation2024240120252647580Copyright © Шкарубо А.Н., Трунин Ю.Ю., Чернов И.В., Калинин П.Л., 20252025Шкарубо А.Н., Трунин Ю.Ю., Чернов И.В., Калинин П.Л.Shkarubo A.N., Trunin Y.Y., Chernov I.V., Kalinin P.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therjn.com/jour/article/view/1612

   Сочетание аденом гипофиза по отдельности с менингиомами или вестибулярными шванномами – достаточно редкое событие: в литературе описаны лишь единичные случаи или небольшие серии наблюдений. В статье представлено редкое клиническое наблюдение пациентки, оперированной и получившей лучевую терапию по поводу гормонально неактивной аденомы гипофиза, у которой при катамнестическом обследовании выявлен нейрофиброматоз 2-го типа (интракраниальные менингиома и невринома (шваннома)). Сочетание гистологически различных интракраниальных опухолей (аденомы гипофиза, менингиомы и невриномы) является крайне редким и требует соответствующих подходов к лечению.

   Combination of pituitary adenomas with meningiomas or vestibular schwannomas is a rare occurrence: in scientific literature, only individual cases or small case series are described. The article presents a rare clinical observation of a female patient who underwent surgery and radiotherapy due to hormonally inactive pituitary adenoma and neurofibromatosis type 2 (intracranial meningioma and neurinoma (schwannoma)) found during a follow-up exam. A combination of histologically different intracranial tumors (pituitary adenoma, meningioma, and neurinoma) is extremely rare and requires corresponding approaches to treatment.

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The authors declare that there are no conflicts of interest present.