Intrathecal baclofen therapy in the management of drug-resistant muscle spasticity in patients with traumatic spinal cord injury
https://doi.org/10.17650/1683-3295-2021-23-4-44-49
Abstract
Neurorehabilitation of patients with spinal cord injury and severe muscle spasticity have always been one of the most challenging tasks for neurologists. Muscle spasticity significantly impairs patients’ quality of life and is often resistant to pharmacotherapy. Over the last 10 years, intrathecal baclofen therapy has become the most effective treatment for spasticity in Russia. In this study, we tried to systematize the data on intrathecal baclofen therapy in patients with spinal cord injury complicated by spasticity and to evaluate their treatment outcomes, as well as the incidence of adverse events. Our findings will ultimately help to clarify the need for intrathecal baclofen therapy in routine clinical practice.
About the Authors
I. N. Morozov
Center for Neurorehabilitation of Patients with Spinal Cord Pathology, Privolzhsky Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Ivan Nikolaevich Morozov
10/1 Ploshchad Minina i Pozharskogo, Nizhny Novgorod 603005
E. D. Isagulyan
N.N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
16 4 th Tverskaya-Yamskaya St., Moscow 125047
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For citations:
Morozov I.N., Isagulyan E.D. Intrathecal baclofen therapy in the management of drug-resistant muscle spasticity in patients with traumatic spinal cord injury. Russian journal of neurosurgery. 2021;23(4):44-49. (In Russ.) https://doi.org/10.17650/1683-3295-2021-23-4-44-49
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