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Биохимические маркеры черепно-мозговой травмы

https://doi.org/10.17650/1683-3295-2014-0-2-83-91

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Аннотация

Представлен обзор литературы, посвященный современным биохимическим маркерам, применяемым при диагностике, оценке эффективности лечения и прогнозе исходов у пострадавших с черепномозговой травмой (ЧМТ). Изложены основные требования, предъявляемые на сегодняшний день к современным биохимическим маркерам. Подробно описаны преимущества, недостатки и область применения наиболее изученных и используемых в клинической практике биохимических маркеров ЧМТ: протеина S-100β, нейрон-специфической енолазы, глиального фибриллярного кислого протеина, протеина С-tau, продуктов распада спектрина и маркеров апоптоза (каспазы-3, протеина Fas и белков bcl-2).

Об авторах

Евгений Александрович Сосновский
Московский государственный медико-стоматологический университет им. А.И. Евдокимова
Россия


Юлия Владимировна Пурас
НИИ скорой помощи им. Н.В. Склифосовского
Россия


Александр Эрнестович Талыпов
НИИ скорой помощи им. Н.В. Склифосовского
Россия


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Для цитирования:


Сосновский Е.А., Пурас Ю.В., Талыпов А.Э. Биохимические маркеры черепно-мозговой травмы. Нейрохирургия. 2014;(2):83-91. https://doi.org/10.17650/1683-3295-2014-0-2-83-91

For citation:


Sosnovsky E.A., Puras J.V., Talypov A.E. Biochemical markers of head injury. Russian journal of neurosurgery. 2014;(2):83-91. (In Russ.) https://doi.org/10.17650/1683-3295-2014-0-2-83-91

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