One-stage combined removal of a large endo-, supra-, infra-, retro-, ante-, and latero(S)sellar somatotroph adenoma
https://doi.org/10.63769/1683-3295-2026-28-2-82-87
Abstract
Endoscopic endonasal approach is an effective method for pituitary adenomas removing, including tumors with significant intracranial extension. However, with complex growth variants, it becomes impossible to use onle this approach. The modern development of endoscopic technologies in neurosurgery and achievements in neuroanesthesiology allow performing the simultaneous combined (transcranial-transnasal) interventions for pituitary adenomas with complex tumor extension.
This article presents a clinical case demonstrating the treatment of a patient with a hormone-active pituitary adenoma (somatotropinoma) characterized by expressed supra- and laterosellar growth patterns. The possibility of simultaneous removal of large pituitary adenomas using a combined one-stage (transcranial and transnasal approaches) intervention with a good outcome has been demonstrated.
About the Authors
O. Yu. Bogdanova
Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department; National Medical Research Center for Otorhinolaryngology, Federal Medical Biological Agency of Russia; Russian Сenter of Neurology and Neurosciences
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Ploshchad
Build. 2, 30 Volokolamskoye Shosse, Moscow 123182
80 Volokolamskoye Shosse, Moscow 125367
V. A. Grigoryev
Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Vladislav Andreyevich Grigoryev
1 Ostrovityanova St., Moscow 117513
V. V. Krylov
Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department; National Medical Research Center for Otorhinolaryngology, Federal Medical Biological Agency of Russia; Russian Сenter of Neurology and Neurosciences; Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Ploshchad
Build. 2, 30 Volokolamskoye Shosse, Moscow 123182
80 Volokolamskoye Shosse, Moscow 125367
1 Ostrovityanova St., Moscow 117513
A. Yu. Grigoryev
Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department; National Medical Research Center for Endocrinology, Ministry of Health of Russia
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Ploshchad, Moscow 129090
11 Dmitriya Ulyanova St., Moscow 117292
A. A. Grin
Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Ploshchad, Moscow 129090
References
1. Kalinin P.L., Kadashev B.A., Fomichev D.V. et al. Surgical treatment of pituitary adenomas. Clinical guidelines. Mosсow, 2014. P. 19–21. (In Russ.).
2. Kuo C.H., Yen Y.S., Wu J.C. et al. Primary endoscopic transnasal transsphenoidal surgery for giant pituitary adenoma. World Neurosurg 2016;91:121–8. DOI: 10.1016/j.wneu.2016.03.092
3. Gondim J.A., Almeida J.P., Albuquerque L.A. et al. Giant pituitary adenomas: surgical outcomes of 50 cases operated on by the endonasal endoscopic approach. World Neurosurg 2014;82(1-2):e281–90. DOI: 10.1016/j.wneu.2013.08.028
4. Koutourousiou M., Gardner P.A., Fernandez-Miranda J.C. et al. Endoscopic endonasal surgery for giant pituitary adenomas: advantages and limitations. J Neurosurg 2013;118(3):621–31. DOI: 10.3171/2012.11.JNS121190
5. Alleyne C.H.Jr, Barrow D.L., Oyesiku N.M. Combined transsphenoidal and pterional craniotomy approach to giant pituitary tumors. Surg Neurol 2002;57(6):380–90. DOI: 10.1016/s0090-3019(02)00705-x
6. Inoue A., Suehiro S., Ohnishi T. et al. Simultaneous combined endoscopic endonasal and transcranial surgery for giant pituitary adenomas: tips and traps in operative indication and procedure. Clin Neurol Neurosurg 2022;218:107281. DOI: 10.1016/j.clineuro.2022.107281
7. Kuga D., Toda M., Ozawa H. et al. Endoscopic endonasal approach combined with a simultaneous transcranial approach for giant pituitary tumors. World Neurosurg 2019;121:173–9. DOI: 10.1016/j.wneu.2018.10.047
8. Leung G.K.K., Law H.Y., Hung K.N. et al. Combined simultaneous transcranial and transsphenoidal resection of large-to-giant pituitary adenomas. Acta Neurochir (Wien) 2011;153(7):1401–8. DOI: 10.1007/s00701-011-1029-y
Review
For citations:
Bogdanova O.Yu., Grigoryev V.A., Krylov V.V., Grigoryev A.Yu., Grin A.A. One-stage combined removal of a large endo-, supra-, infra-, retro-, ante-, and latero(S)sellar somatotroph adenoma. Russian journal of neurosurgery. 2026;28(2):82-87. (In Russ.) https://doi.org/10.63769/1683-3295-2026-28-2-82-87
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