HYPOTHALAMIC HAMARTOMA. LITERATURE REVIEW
https://doi.org/10.17650/1683-3295-2019-21-2-94-106
Abstract
The study objective is to analyze scientific literature on hypothalamic hamartomas’ diagnostics and treatment.
Materials and methods. We studied 90 scientific sources, published between 1948 and 2019.
Results. The paper describes clinical picture of hypothalamic hamartomas, their various classifications, specificity of neuroimaging and neurophysiological diagnostics and pathomorphological research, the surgical treatment.
Conclusion. Transnasal resection is a promising and noninvasive method to treat hypothalamic hamartomas of IV and V types by J. Régis classification. According to the scientific literature, stereotactic destruction can be used to resect hamartomas of I–IV types; types II and III require endoscopic transventricular approach, while types IV and V can be resected using endoscopic transnasal transsphenoidal approach.
About the Authors
А. Yu. Grigoriev
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; National Medical Research Center of Endocrinology, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473;
11 Dmitriya Ul’yanova St., Moscow 117036
М. V. Sinkin
N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department
Russian Federation
3 Bol’shaya Sukharevskaya Sq., Moscow 129090
Russian Federation
3 Bol’shaya Sukharevskaya Sq., Moscow 129090
Е. V. Grigorieva
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
I. S. Trifonov
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
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Grigoriev А.Yu., Sinkin М.V., Grigorieva Е.V., Trifonov I.S. HYPOTHALAMIC HAMARTOMA. LITERATURE REVIEW. Russian journal of neurosurgery. 2019;21(2):94-106. (In Russ.) https://doi.org/10.17650/1683-3295-2019-21-2-94-106
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