SURGICAL TREATMENT OF MRI-NEGATIVE EPILEPSY (A REVIEW)
https://doi.org/10.17650/1683-3295-2019-21-2-76-84
Abstract
Removal of epileptogenic lesions is an effective way to treat patients with drug-resistant epilepsy. The result of surgical treatment depends on the correct detection of pathology, definition of its boundaries. No lesion on magnetic resonance imaging is not a contraindication to surgical treatment, but requires a survey. Each of the additional methods has its advantages and disadvantages. Сomprehensive examination, analysis and comparison of positron emission tomography, single-photon emission computed tomography, magnetoencephalography, scalp and invasive electroencephalography data can significantly improve the results of surgical treatment MRI-negative epilepsy patients. Clarification of the pre-surgical evaluation algorithm will allow to optimize the use of techniques.
About the Authors
I. S. Trifonov
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
O. O. Kordonskaya
N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department
Russian Federation
3 Bol’shaya Sukharevskaya Sq., Moscow 129090
Russian Federation
3 Bol’shaya Sukharevskaya Sq., Moscow 129090
M. V. Sinkin
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department
Russian Federation
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473;
3 Bol’shaya Sukharevskaya Sq., Moscow 129090
E. V. Grigorieva
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
Russian Federation
Bld. 1, 20 Delegatskaya St., Moscow 127473
References
1. Крылов В.В., Гехт А.Б., Трифонов И.С. и др. Клинические рекомендации по предоперационному обследованию и хирургическому лечению пациентов с фармакорезистентными формами эпилепсии. М., 2015. 22 с. [Krylov V.V., Gekht A.B., Trifonov I.S. et al. Preoperative examination and surgical treatment of patients with drug-resistant epilepsy. Clinical guidelines. Moscow, 2015. 22 p. (In Russ.)].
2. Kwan P., Schachter S.C., Brodie M.J. Drug-resistant epilepsy. N Engl J Med 2011;365(10):919–26. DOI: 10.1056/NEJMra1004418.
3. Wiebe S., Blume W.T., Girvin J.P. et al. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 2001;345(5):311–8. DOI: 10.1056/NEJM200108023450501.
4. Muhlhofer W., Tan Y.L., Mueller S.G., Knowlton R. MRI-negative temporal lobe epilepsy – what do we know? Epilepsia 2017;58(5):727–42. DOI: 10.1111/epi.13699.
5. Крылов В.В., Гехт А.Б., Трифонов И.С. и др. Исходы хирургического лечения пациентов с фармакорезистентными формами эпилепсии. Журнал неврологии и психиатрии им. С.С. Корсакова 2016;116(9-2):13–8. [Krylov V.V., Gekht A.B., Trifonov I.S. et al. Outcomes of surgical treatment of patients with pharmacoresistant epilepsy. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova = S.S. Korsakov Journal of Neurology and Psychiatry 2016;116(9-2):13–8. (In Russ.)]. DOI: 10.17116/jnevro20161169213-18.
6. Téllez-Zenteno J.F., Hernández Ronquillo L., Moien-Afshari F., Wiebe S. Surgical outcomes in lesional and non-lesional epilepsy: a systematic review and metaanalysis. Epilepsy Res 2010;89(2):310–8. DOI: 10.1016/j.eplepsyres.2010.02.007.
7. Berg A.T., Vickrey B.G., Langfitt J.T. et al. The multicenter study of epilepsy surgery: recruitment and selection for surgery. Epilepsia 2003;44(11):1425–33.
8. Urbach H., Hattingen J., von Oertzen J. et al. MR imaging in the presurgical workup of patients with drug-resistant epilepsy. AJNR Am J Neuroradiol 2004;25(6):919–26.
9. MRI-negative epilepsy. Evaluation and surgical management. Ed. by E.L. So, P. Ryvlin. Cambridge University Press, 2015. 425 p. DOI: 10.1017/CBO9781139525312.
10. Bien C.G., Szinay M., Wagner J. et al. Characteristics and surgical outcome of patients with refractory magnetic resonance imaging-negative epilepsies. Arch Neurol 2009;66(12):1491–9. DOI: 10.1001/archneurol.2009.283.
11. Крылов В.В., Гехт А.Б., Трифонов И.С. и др. Хирургическое лечение больных с магнитно-резонансно-негативными фармакорезистентными формами эпилепсии. Неврологический журнал 2016;21(4):213–8. [Krylov V.V., Gekht A.B., Trifonov I.S. et al. Surgical treatment of patients with magnetic resonance-negative drug-resistant forms of epilepsy. Nevrologichesky zhurnal = Neurological Journal 2016;21(4):213–8. (In Russ.)]. DOI: 10/18821/1560-9545-2016-21-4-213-218.
12. Widdess-Walsh P., Diehl B., Najm I. Neuroimaging of focal cortical dysplasia. J Neuroimaging 2006;16(3):185–96. DOI: 10.1111/j.1552-6569.2006.00025.x.
13. Wang Z.I., Alexopoulos A.V., Jones S.E. et al. The pathology of magneticresonance-imaging-negative epilepsy. Mod Pathol 2013;26(8):1051–8. DOI: 10.1038/modpathol.2013.52.
14. Bell M.L., Rao S., So E.L. et al. Epilepsy surgery outcomes in temporal lobe epilepsy with a normal MRI. Epilepsia 2009;50(9):2053–60. DOI: 10.1111/j.1528-1167.2009.02079.x.
15. Winston G.P., Micallef C., Kendell B.E. et al. The value of repeat neuroimaging for epilepsy at a tertiary referral centre: 16 years of experience. Epilepsy Res 2013;105(3):349–55. DOI: 10.1016/j.eplepsyres.2013.02.022.
16. Chassoux F., Semah F., Bouilleret V. et al. Metabolic changes and electro-clinical patterns in mesio-temporal lobe epilepsy: a correlative study. Brain 2004; 127(Pt 1):164–74. DOI: 10.1093/brain/awh014.
17. Knake S., Triantafyllou C., Wald L.L. et al. 3T phased array MRI improves the presurgical evaluation in focal epilepsies: a prospective study. Neurology 2005;65(7):1026–31. DOI: 10.1212/01.wnl.0000179355.04481.3c.
18. Nguyen D.K., Rochette E., Leroux J.M. et al. Value of 3.0 T MR imaging in refractory partial epilepsy and negative 1.5 T MRI. Seizure 2010;19(8):475–8. DOI: 10.1016/j.seizure.2010.07.002.
19. Textbook of epilepsy surgery. Ed. by H. Ludors. Informa UK Ltd, 2008. 1582 p.
20. Willmann O., Wennberg R., May T. et al. The contribution of 18F-FDG PET in preoperative epilepsy surgery evaluation for patients with temporal lobe epilepsy: a meta-analysis. Seizure 2007;16(6):509–20. DOI: 10.1016/j.seizure.2007.04.001.
21. LoPinto-Khoury C., Sperling M.R., Skidmore C. et al. Surgical outcome in PET-positive, MRI‐negative patients with temporal lobe epilepsy. Epilepsia 2012;53(2):342–48. DOI: 10.1111/j.1528-1167.2011.03359.x.
22. Immonen A., Jutila L., Muraja-Murro A. et al. Long-term epilepsy surgery outcomes in patients with MRI-negative temporal lobe epilepsy. Epilepsia 2010;51(11):2260–9. DOI: 10.1111/j.1528-1167.2010.02720.x.
23. Theodore W.H., Newmark M.E., Sato S. et al. [18F]fluorodeoxyglucose positron emission tomography in refractory complex partial seizures. Ann Neurol 1983;14(4):429–37. DOI: 10.1002/ana.410140406.
24. Wang Z.I., Alexopoulos A.V., Jones S.E. et al. Linking MRI postprocessing with magnetic source imaging in MRI-negative epilepsy. Ann Neurol 2014;75(5):759–70. DOI: 10.1002/ana.24169.
25. Weil S., Noachtar S., Arnold S. et al. Ictal ECD-SPECT differentiates between temporal and extratemporal epilepsy: confirmation by excellent postoperative seizure control. Nucl Med Commun 2001;22(2):233–7.
26. Van Paessechen W. Ictal SPECT. Epilepsia 2004;45(4):34–40. DOI: 10.1111/j.0013-9580.2004.04008.x.
27. Sulc V., Stykel S., Hanson D.P. et al. Statistical SPECT processing in MRInegative epilepsy surgery. Neurology 2014;82(11):932–9. DOI: 10.1212/WNL.0000000000000209.
28. Kazemi N.J., Worrell G.A., Stead S.M. et al. Ictal SPECT statistical parametric mapping in temporal lobe epilepsy surgery. Neurology 2010;74(1):70–6. DOI: 10.1212/WNL.0b013e3181c7da20.
29. Schmeiser B., Zentner J., Steinhoff B.J. et al. The role of presurgical EEG parameters and of reoperation for seizure outcome in temporal lobe epilepsy. Seizure 2017;51:174–9. DOI: 10.1016/j.seizure.2017.08.015.
30. Raghavendra S., Nooraine J., Mirsattari S.M. Role of electroencephalography in presurgical evaluation of temporal lobe epilepsy. Epilepsy Res Treat 2012;2012: 204693. DOI: 10.1155/2012/204693.
31. So N.K., Engel J. Jr, Williamson P.D. et al. Depth electrodes. In: Surgical treatment of the epilepsies. Ed. by J. Engel. New York: Raven Press, 1993. Pp. 359–376.
32. Harroud A., Bouthillier A., Weil A.G., Nguyen DK. Temporal lobe epilepsy surgery failures: a review. Epilepsy Res Treat 2012;2012:201651. DOI: 10.1155/2012/201651.
33. Rosati A., Aghakhani Y., Bernasconi A. Tao J.X., Baldwin M., Hawes-Ebersole S., Ebersole J.S. Cortical substrates of scalp EEG epileptiform discharges. J Clin Neurophysiol 2007;24(2):96–100. DOI: 10.1097/wnp.0b013e31803ecdaf.
34. Blume W.T., Ganapathy G.R., Munoz D., Lee D.H. Indices of resective surgery effectiveness for intractable nonlesional focal epilepsy. Epilepsia 2004;45(1):46–53.
35. Sadler M., Desbiens R. Scalp EEG in temporal lobe epilepsy surgery. Can J Neurol Sci 2000; 27(Suppl 1):S22–8.
36. Lee S.K., Yun C.H., Oh J.B. et al. Intracranial ictal onset zone in nonlesional lateral temporal lobe epilepsy on scalp ictal EEG. Neurology 2003;61(6):757–64.
37. Aghakhani Y, Liu X, Jette N, Wiebe S. Epilepsy surgery in patients with bilateral temporal lobe seizures: a systematic review. Epilepsia 2014;55(12):1892–901. DOI: 10.1111/epi.12856.
38. Widdess-Walsh P., Jeha L., Nair D. et al. Subdural electrode analysis in focal cortical dysplasia: predictors of surgical outcome. Neurology 2007;69(7):660–7. DOI: 10.1212/01.wnl.0000267427.91987.21.
39. Lee S.K., Kim K.K., Nam H. et al. Adding or repositioning intracranial electrodes during presurgical assessment of neocortical epilepsy: electrographic seizure pattern and surgical outcome. J Neurosurg 2004;100(3):463–71. DOI: 10.3171/jns.2004.100.3.0463.
40. Tonini C., Beghi E., Berg A.T. et al. Predictors of epilepsy surgery outcome: a meta-analysis. Epilepsy Res 2004;62(1):75–87. DOI: 10.1016/j.eplepsyres.2004.08.006.
41. Barba C., Rheims S., Minotti L. et al. Temporal plus epilepsy is a major determinant of temporal lobe surgery failures. Brain 2015;139(Pt 2):444–51. DOI: 10.1093/brain/awv372.
42. Wiebe S. Early epilepsy surgery. Curr Neurol Neurosci Rep 2004;4(4):315–20.
43. Reuber M., Andersen B., Elger C.E., Helmstaedter C. Depression and anxiety before and after temporal lobe epilepsy surgery. Seizure 2004;13(2):129–35.
44. Shorvon S., Tomson T. Sudden unexpected death in epilepsy. Lancet 2011;378(9808):2028–38. DOI: 10.1016/S0140-6736(11)60176-1.
Review
For citations:
Trifonov I.S., Kordonskaya O.O., Sinkin M.V., Grigorieva E.V. SURGICAL TREATMENT OF MRI-NEGATIVE EPILEPSY (A REVIEW). Russian journal of neurosurgery. 2019;21(2):76-84. (In Russ.) https://doi.org/10.17650/1683-3295-2019-21-2-76-84
Views:
1341
Email this article 