Langerhans cell histiocytosis (eosinophilic granuloma) with the orbital roof lesion: clinical observation
https://doi.org/10.63769/1683-3295-2025-27-4-74-79
Abstract
Eosinophilic granuloma represents a subtype of histiocytosis, a benign tumor-like condition characterized by aberrant proliferation of antigenpresenting Langerhans cells derived from dendritic cells. This article presents a clinical case of a patient admitted with complaints of left upper eyelid edema and pain in the periorbital and temporal regions. Imaging studies revealed an intraosseous soft tissue lesion on the left side of the orbital roof. Surgical excision of the tumor was performed, and histological analysis of the biopsy specimen confirmed the diagnosis of eosinophilic granuloma.
About the Authors
A. A. Pichugin
Kazan State Medical University, Ministry of Health of Russia; Interregional Clinical Diagnostic Center
Россия
Россия
Arseniy Anatolyevich Pichugin
49 Butlerova St., Kazan 420012;
12A Karbysheva St., Kazan 420101
K. M. Khairullina
Kazan State Medical University, Ministry of Health of Russia
Россия
Россия
49 Butlerova St., Kazan 420012
T. A. Nemirovskaya
Russian Medical Academy of Continuous Professional Education, Ministry of Health of Russia
Россия
Россия
2/1 Barrikadnaya St., Moscow 125993
A. G. Alexeev
Kazan State Medical University, Ministry of Health of Russia; Interregional Clinical Diagnostic Center
Россия
Россия
49 Butlerova St., Kazan 420012;
12A Karbysheva St., Kazan 420101
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Review
For citations:
Pichugin A.A., Khairullina K.M., Nemirovskaya T.A., Alexeev A.G. Langerhans cell histiocytosis (eosinophilic granuloma) with the orbital roof lesion: clinical observation. Russian journal of neurosurgery. 2025;27(4):74-79. (In Russ.) https://doi.org/10.63769/1683-3295-2025-27-4-74-79
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