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Нейрохирургия

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ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ИЗУЧЕНИЯ СОСУДИСТОГО СПАЗМА ПРИ НЕТРАВМАТИЧЕСКОМ СУБАРАХНОИДАЛЬНОМ КРОВОИЗЛИЯНИИ IN VIVO

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Аннотация

Проведен анализ данных литературы по моделированию сосудистого спазма при нетравматических субарахноидальных кровоизлияниях на различных лабораторных животных (обезьяны, собаки, крысы). Обсуждены основные методики моделирования спазма, особенности его оценки в эксперименте, сопоставимость результатов экспериментальных данных с клиническими. Рассмотрена потенциальная возможность изучения различных способов профилактики и лечения сосудистого спазма на конкретных биологических моделях. Отдельное внимание уделено особенностям моделирования спазма у «небольших» лабораторных животных, в частности крыс.

Об авторах

Александр Владиславович Природов
НИИ скорой помощи им. Н.В. Склифосовского
Россия


Евгений Юрьевич Бахарев
НИИ скорой помощи им. Н.В. Склифосовского
Россия


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Для цитирования:


Природов А.В., Бахарев Е.Ю. ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ИЗУЧЕНИЯ СОСУДИСТОГО СПАЗМА ПРИ НЕТРАВМАТИЧЕСКОМ СУБАРАХНОИДАЛЬНОМ КРОВОИЗЛИЯНИИ IN VIVO. Нейрохирургия. 2014;(3):65-70.

For citation:


Prirodov A.V., Bakharev E.Y. The experimental models for examination of angiospasm because of non-traumatic subarachnoid hemorrhage in vivo. Russian journal of neurosurgery. 2014;(3):65-70. (In Russ.)

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