ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ИЗУЧЕНИЯ СОСУДИСТОГО СПАЗМА ПРИ НЕТРАВМАТИЧЕСКОМ СУБАРАХНОИДАЛЬНОМ КРОВОИЗЛИЯНИИ IN VIVO
Аннотация
Проведен анализ данных литературы по моделированию сосудистого спазма при нетравматических субарахноидальных кровоизлияниях на различных лабораторных животных (обезьяны, собаки, крысы). Обсуждены основные методики моделирования спазма, особенности его оценки в эксперименте, сопоставимость результатов экспериментальных данных с клиническими. Рассмотрена потенциальная возможность изучения различных способов профилактики и лечения сосудистого спазма на конкретных биологических моделях. Отдельное внимание уделено особенностям моделирования спазма у «небольших» лабораторных животных, в частности крыс.
Об авторах
Александр Владиславович Природов
НИИ скорой помощи им. Н.В. Склифосовского
Россия
Россия
Евгений Юрьевич Бахарев
НИИ скорой помощи им. Н.В. Склифосовского
Россия
Россия
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Рецензия
Для цитирования:
Природов А.В., Бахарев Е.Ю. ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ИЗУЧЕНИЯ СОСУДИСТОГО СПАЗМА ПРИ НЕТРАВМАТИЧЕСКОМ СУБАРАХНОИДАЛЬНОМ КРОВОИЗЛИЯНИИ IN VIVO. Нейрохирургия. 2014;(3):65-70.
For citation:
Prirodov A.V., Bakharev E.Yu. The experimental models for examination of angiospasm because of non-traumatic subarachnoid hemorrhage in vivo. Russian journal of neurosurgery. 2014;(3):65-70. (In Russ.)
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