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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/1683-3295-2020-22-4-112-122</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-969</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Тромбоэмболические осложнения в нейрохирургии: решения на границе возможного и необходимого (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Thromboembolic complications in neurosurgery: solutions at the boundaries of possible and necessary (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9034-2212</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бервицкий</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bervitskiy</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анатолий Владимирович Бервицкий</p><p>630087 Новосибирск, ул. Пемировича-Данченка, 132/1; 630060 Новосибирск, ул. Тимакова, 2; 630090 Новосибирск, просп. Лаврентьева, 15</p></bio><bio xml:lang="en"><p>132/ 1 Nemirovicha-Danchenko St., Novosibirsk 630087; 2 Timakova St., Novosibirsk 630060; 15 Lavrentieva Ave., Novosibirsk 630090</p></bio><email xlink:type="simple">a_bervitskiy@neuronsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гужин</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Guzhin</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630087 Новосибирск, ул. Пемировича-Данченка, 132/1</p></bio><bio xml:lang="en"><p>132/ 1 Nemirovicha-Danchenko St., Novosibirsk 630087</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3885-3004</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мойсак</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moisak</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630087 Новосибирск, ул. Пемировича-Данченка, 132/1; 630090 Новосибирск, ул. Пирогова, 1</p></bio><bio xml:lang="en"><p>132/ 1 Nemirovicha-Danchenko St., Novosibirsk 630087; 1 Pirogova St., Novosibirsk 630090</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабченко</surname><given-names>В. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Babchenko</surname><given-names>V. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1209-8960</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рзаев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rzaev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630087 Новосибирск, ул. Пемировича-Данченка, 132/1; 630090 Новосибирск, ул. Пирогова, 1</p></bio><bio xml:lang="en"><p>132/ 1 Nemirovicha-Danchenko St., Novosibirsk 630087; 1 Pirogova St., Novosibirsk 630090</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Федеральный центр нейрохирургии Минздрава России (Новосибирск); Научно-исследовательский институт клинической и экспериментальной лимфологии — филиал ФГБНУ Институт цитологии и генетики Сибирского отделения, Российская академия наук; ФГБУН Институт гидродинамики им. М.А. Лаврентьева, Сибирское отделение Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Neurosurgical Center (Novosibirsk), Ministry of Health of Russia; Research Institute of Clinical and Experimental Lymphology — branch of the Institute of Cytology and Genetics, Siberian branch of Russian Academy of Sciences; Lavrentyev Institute of Hydrodynamics, Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Федеральный центр нейрохирургии Минздрава России (Новосибирск)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Neurosurgical Center (Novosibirsk), Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ Федеральный центр нейрохирургии Минздрава России (Новосибирск); ФГАОУ ВО Новосибирский национальный исследовательский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Neurosurgical Center (Novosibirsk), Ministry of Health of Russia; Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО Новосибирский национальный исследовательский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>01</month><year>2021</year></pub-date><volume>22</volume><issue>4</issue><fpage>112</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бервицкий А.В., Гужин В.Э., Мойсак Г.И., Бабченко В.Я., Рзаев Д.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Бервицкий А.В., Гужин В.Э., Мойсак Г.И., Бабченко В.Я., Рзаев Д.А.</copyright-holder><copyright-holder xml:lang="en">Bervitskiy A.V., Guzhin V.E., Moisak G.I., Babchenko V.Y., Rzaev D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/969">https://www.therjn.com/jour/article/view/969</self-uri><abstract><p>Венозные тромбоэмболические осложнения (ВТЭО) — актуальная проблема всех хирургических специальностей, и нейрохирургия не стала исключением. Данные о частоте послеоперационного тромбоза глубоких вен и тромбоэмболии легочной артерии варьируют в широком диапазоне: от 0 до 34 % и от 0 до 3,8 % соответственно. По некоторым оценкам, ВТЭО стоят на 2-м месте среди причин летальных исходов после нейрохирургических операций, что делает изучение данной проблемы крайне важным для улучшения качества медицинской помощи. Обзор обобщает данные современной научной литературы о частоте ВТЭО, а также о патогенезе, стратификации риска и методах профилактики тромбоза глубоких вен и тромбоэмболии легочной артерии.</p></abstract><trans-abstract xml:lang="en"><p>Venous thromboembolic complications (VTE) are an actual problem for all surgical specialties, and neurosurgery was no exception. Data on the incidence of deep vein thrombosis and pulmonary embolism vary over a wide range: from 0 to 34 % andfrom 0 to 3.8 %, respectively. According to some estimates, VTE are in second place among the causes of postoperative mortality in neurosurgery, which makes the study of this topic relevant and undoubtedly important for improving the quality of care for patients. The article provides an overview of modern scientific literature, relevant data on the frequency of occurrence of VTE. The issues of pathogenesis, risk stratification and methods for the prevention of deep vein thrombosis and pulmonary embolism are highlighted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>осложнения</kwd><kwd>тромбоз глубоких вен</kwd><kwd>тромбоэмболия легочной артерии</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>complications</kwd><kwd>deep vein thrombosis</kwd><kwd>pulmonary embolism</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hamilton M.G., Hull R.D., Pineo G.F. 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