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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-83</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>ХИРУРГИЧЕСКИЕ МЕТОДЫ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ СОСУДИСТОГО СПАЗМА У БОЛЬНЫХ ПОСЛЕ РАЗРЫВА АНЕВРИЗМ СОСУДОВ ГОЛОВНОГО МОЗГА</article-title><trans-title-group xml:lang="en"><trans-title>The surgical methods for prevention and treatment of cerebral angiospasm at patients suffered from rupture of cerebral aneurysms</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крылов</surname><given-names>Владимир Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Krylov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Природов</surname><given-names>Александр Владиславович</given-names></name><name name-style="western" xml:lang="en"><surname>Prirodov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">aprirodov@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Т. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetcova</surname><given-names>T. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МГМСУ им. А.И. Евдокимова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>НИИ скорой помощи им. Н.В. Склифосовского</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Научно-практический центр медицинской помощи детям с пороками развития черепно-лицевой области и врожденными заболеваниями нервной системы ДЗ г. Москвы</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>104</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крылов В.В., Природов А.В., Кузнецова Т.К., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Крылов В.В., Природов А.В., Кузнецова Т.К.</copyright-holder><copyright-holder xml:lang="en">Krylov V.V., Prirodov A.V., Kuznetcova T.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/83">https://www.therjn.com/jour/article/view/83</self-uri><abstract><p>В представленном обзоре рассмотрена проблема профилактики и лечения сосудистого спазма у больных с разрывом артериальных аневризм головного мозга. В работе рассмотрены основные механизмы патогенеза вазоспазма, факторы риска его развития. Обсуждаются методики профилактики и лечения спазма, их эффективность и безопасность у больных с нетравматическим субарахноидальным кровоизлиянием. Среди них наибольшее внимание уделено интрацистернальному и внутрижелудочковому введению фармакологических препаратов, в том числе фибринолитиков и вазодилататоров, и транслюминальной баллонной ангиопластике спазмированных артерий. Представлены результаты проводимых исследований.</p></abstract><trans-abstract xml:lang="en"><p>This literature review presents the problem of prevention and treatment of angiospasm at patients with ruptured cerebral aneurysms as well as enlights the main mechanisms of angiospasm pathogenesis and risk factors. The various methods for prevention and treatment of angiospasm as well as their efficacy and safety at patients with non-traumatic subarachnoid hemorrhage (SAH) are discussed. The main attention is paid for intracisternal and intraventricular introduction of drugs, such as vasodilators and fibrinolytics, as well as for transluminal balloon angioplasty of affected arteries. The data of conducting trials are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сосудистый спазм</kwd><kwd>артериальная аневризма</kwd><kwd>вазодилататоры</kwd><kwd>фибринолитики</kwd><kwd>транслюминальная баллонная ангиопластика</kwd><kwd>angiospasm</kwd><kwd>cerebral aneurysm</kwd><kwd>vasodilators</kwd><kwd>fibrinolytics</kwd><kwd>transluminal balloon angioplasty</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ворлоу Ч.П., Деннис М.С., Ван Гейн Ж., Ханкий Г.Ж., Сандеркок П.А.Г., Бамфорд Ж.М., Вордлау Ж. Инсульт: практическое руководство для врачей. 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