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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/1683-3295-2018-20-3-31-38</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-600</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ РАБОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>Результаты хирургического лечения пациентов с эндокринной офтальмопатией с применением минимально инвазивных методов</article-title><trans-title-group xml:lang="en"><trans-title>Results of surgical treatment using minimally invasive methods in patients with endocrine ophthalmopathy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0857-9398</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левченко</surname><given-names>О. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Levchenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4161-0940</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каландари</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalandari</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алик Амиранович Каландари</p><p>127473 Москва, ул. Делегатская, 20, стр. 1;</p></bio><bio xml:lang="en"/><email xlink:type="simple">kalandarialik@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3202-570X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутровская</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutrovskaya</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9575-4520</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoriev</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5740-9091</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Timofeeva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4811-0845</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8207-7180</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigorieva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ревазян</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Revazyan</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Endocrinology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ «Эндокринологический диспансер Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology dispensary, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>19</day><month>09</month><year>2018</year></pub-date><volume>20</volume><issue>3</issue><fpage>31</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Левченко О.B., Каландари А.А., Кутровская Н.Ю., Григорьев А.Ю., Тимофеева О.Н., Левина О.А., Григорьева Е.В., Ревазян К.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Левченко О.B., Каландари А.А., Кутровская Н.Ю., Григорьев А.Ю., Тимофеева О.Н., Левина О.А., Григорьева Е.В., Ревазян К.В.</copyright-holder><copyright-holder xml:lang="en">Levchenko O.V., Kalandari A.A., Kutrovskaya N.Y., Grigoriev A.Y., Timofeeva O.N., Levina O.A., Grigorieva E.V., Revazyan K.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/600">https://www.therjn.com/jour/article/view/600</self-uri><abstract><p>Цель исследования – провести анализ результатов хирургического лечения пациентов с эндокринной офтальмопатией с использованием минимально инвазивных трансорбитальных доступов и с использованием интраоперационного безрамного нейронавигационного наведения.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В основу исследования легли результаты обследования и хирургического лечения 9 больных с эндокринной офтальмопатией (17 орбит) в период с 2015 по 2017 г. На 1-м этапе данные предоперационной компьютерной томографии орбит импортировали в программу навигационной установки, после чего определяли область предполагаемой резекции стенок глазницы. Далее в условиях операционной регистрировали положение головы пациента в системе навигации. Для выполнения костной декомпрессии глазницы и липэктомии мы применяли пресептальный, транскарункулярный и латеральный ретрокантальный доступы, которые являются трансконъюнктивальными и не оставляют послеоперационных рубцов. По завершении костной декомпрессии глазницы ее точность и размеры определяли интраоперационным поинтером нейронавигационной системы.</p></sec><sec><title>Результаты</title><p>Результаты. Послеоперационный период протекал без особенностей. У всех больных по данным клинического осмотра и компьютерной томографии косметические и функциональные результаты были хорошими. Лишь у 1 пациентки после формирования трансконъюнктивального доступа развился симблефарон, что потребовало выполнения реконструкции нижнего века. Других осложнений хирургического лечения зафиксировано не было. Минимальная величина регресса экзофтальма составила 3 мм, максимальная – 7 мм. Двоение в глазах полностью регрессировало у 2 пациентов. Период наблюдения составил 6 мес.</p></sec></abstract><trans-abstract xml:lang="en"><p>The study objective is to analyze the results of surgical treatment of patients with endocrine ophthalmopathy using minimally invasive transorbital approaches and intraoperative frameless neuronavigation.</p><sec><title>Materials and methods</title><p>Materials and methods. The study was based on the results of examination and surgical treatment of 9 patients with endocrine ophthalmopathy (17 orbits) in the period from 2015 to 2017. At the first stage the preoperative computed tomography images of the orbits was imported into the navigation software program, and then the area of the proposed resection of the orbit walls was marked. Further, in the operating room, the patient head position was registered in the navigation system. To perform bone decompression of the orbit and lipectomy, we used preseptal, transcaruncular and lateral retrocanthal approaches. These approaches are transconjunctival and do not leave postoperative scars. Upon completion of the orbitotomy, its accuracy and dimensions were determined by the intraoperative pointer of the neuronavigation system.</p></sec><sec><title>Results</title><p>Results. The postoperative period was uneventful. In all patients, according to clinical examination and computed tomography, good cosmetic and functional results were achieved. Only 1 patient developed a simblypharon after transconjunctival access, which required additional intervention to reconstruct the lower eyelid. There were no other complications of surgical treatment. The minimum degree of regression of exophthalmos was 3 mm, the maximum 7 mm. Diplopia completely regressed in 2 patients. The observation period was 6 months.</p></sec><sec><title>Conclusion</title><p>Conclusion. Minimally invasive transorbital approaches allow the transconjunctival view of all orbital walls to perform decompression of the orbit and lipectomy without cutaneous incisions, to achieve good cosmetic and functional results. The intraoperative use of the neuronavigation system ensures the bone decompression of the orbit in full.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>эндокринная офтальмопатия</kwd><kwd>«сбалансированная» декомпрессия глазницы</kwd><kwd>нейронавигация</kwd><kwd>минимально инвазивные доступы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endocrine ophthalmopathy</kwd><kwd>“balanced” orbital decompression</kwd><kwd>neuronavigation</kwd><kwd>minimally invasive approaches</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fung S., Malhotra R., Selva D. Thyroid orbitopathy. Aust Fam Physician 2003;32(8):615–20. PMID: 12973869.</mixed-citation><mixed-citation xml:lang="en">Fung S., Malhotra R., Selva D. Thyroid orbitopathy. Aust Fam Physician 2003;32(8):615–20. 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