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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-51</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Применение ультранизких температур в нейроонкологии</article-title><trans-title-group xml:lang="en"><trans-title>The usage of ultra-cold temperatures in neuro-oncology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Песня-Прасолов</surname><given-names>Светозар Борисович</given-names></name><name name-style="western" xml:lang="en"><surname>Pesnia-Prasolov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">svetozardr@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>Сергей Амурабиевич</given-names></name><name name-style="western" xml:lang="en"><surname>Vasiliev</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ Российский научный центр хирургии им. акад. Б.В. Петровского РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>3</issue><fpage>92</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Песня-Прасолов С.Б., Васильев С.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Песня-Прасолов С.Б., Васильев С.А.</copyright-holder><copyright-holder xml:lang="en">Pesnia-Prasolov S.V., Vasiliev S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/51">https://www.therjn.com/jour/article/view/51</self-uri><abstract><p>Рассматривается история и современные возможности применения ультранизких температур в нейроонкологии и нейрохирургии, этапы внедрения криохирургии в хирургию опухолей головного мозга как в мире, так и в России. Освещаются возможности современного контроля за процессом криовоздействия и перспективные методы. Рассмотрены основные механизмы криовоздействия на клетку, ткань и сосудистое русло, различные параметры криодеструкции, а также технические факторы, которые могут повлиять на результат криодеструкции. Освещен вопрос криоиммунологических механизмов.</p></abstract><trans-abstract xml:lang="en"><p>There are considered the history and modern possibilities of the usage of ultralow temperature in Russian and World neuro-oncology and neurosurgery (especially for brain tumor removal), the phases of cryosurgery development. The cryotherapy control and its perspective methods are showed. Also there are reviewed main mechanisms of freezing influence on cells, tissues and vasculature, different parameters of cryo-destruction. This article reports about technical factors and possibilities of their influence on the result of cryo-destruction. Cryo-immunology mechanisms are included.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>криохирургия: обзор</kwd><kwd>криодеструкция</kwd><kwd>крио-иммунология</kwd><kwd>замораживание</kwd><kwd>механизмы замораживания</kwd><kwd>cryosurgery: A review</kwd><kwd>cryo-destruction</kwd><kwd>cryo-immunology</kwd><kwd>freezing</kwd><kwd>mechanisms of cryotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Васильев С.А., Крылов В.В., Песня-Прасолов С.Б. и др. Оценка результатов криодеструкции головного мозга млекопитающих (экспериментальная работа) // Хирургия. - 2010. - № 10. - С. 62-68.</mixed-citation><mixed-citation xml:lang="en">Васильев С.А., Крылов В.В., Песня-Прасолов С.Б. и др. 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