<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/1683-3295-2017-0-2-60-65</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-404</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ НЕЙРОХИРУРГИЧЕСКОЙ ПОМОЩИ</subject></subj-group></article-categories><title-group><article-title>К вопросу об организации рентгенхирургической помощи пациентам с острым ишемическим инсультом</article-title><trans-title-group xml:lang="en"><trans-title>Organization of interventional surgery for patients with acute ischemic stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крылов</surname><given-names>Владимир Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Krylov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Володюхин</surname><given-names>Михаил Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Volodyukhin</surname><given-names>M. Yu.</given-names></name></name-alternatives><email xlink:type="simple">voloduckin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МГМСУ им. А.И. Евдокимова; НИИ скорой помощи им. Н.В. Склифосовского</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Межрегиональный клинико-диагностический центр Министерства здравоохранения Республики Татарстан</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>11</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>60</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крылов В.В., Володюхин М.Ю., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Крылов В.В., Володюхин М.Ю.</copyright-holder><copyright-holder xml:lang="en">Krylov V.V., Volodyukhin M.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/404">https://www.therjn.com/jour/article/view/404</self-uri><abstract><p>Цель: Обсуждение современных принципов организации рентгенхирургической помощи пациентам с острым ишемическим инсультом. Материалы и методы: проанализированы современные данные литературы о применении рентген-хирургических технологий у пациентов с острым ишемическим инсультом. Определены основные принципы организации рентгенхирургической помощи у данной категории пациентов. Результаты: ключевыми моментами организации рентгенхирургической помощи являются подготовка специалистов, разработка протоколов и алгоритмов применения рентгенхирургических технологий пациентам с острым ишемическим инсультом, обеспечение аппаратурой и расходным материалом сосудистых центров, где возможно оказывать данный вид помощи. Заключение: Для эффективного внедрения данных технологий в клиническую практику необходимо создание национальных протоколов, определяющих: подготовку специалистов, алгоритм работы «инсультных» команд и оценку показателей качества оказываемой помощи.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to discuss the modern aspects of interventional surgical care organization for patients with acute ischemic stroke. Material and methods: the current literature data concerning usage of interventional techniques in patients with acute ischemic stroke were analyzed. The main principles of interventional surgical care organization for such patients were determined. Results: the key moments for organization of interventional surgery are the follows: specialists training, development of working protocols and algorithms for usage of interventional techniques in patients with acute stroke as well as to provide the techniques and consumable materials for vascular medical centers, where this type of medical care is possible. Conclusion: The national recommendation protocols determined the training of specialists, operation algorithm for «stroke» teams and estimation of medical care efficiency are necessary to be created for effective introduction of such technologies in clinical practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый ишемический инсульт</kwd><kwd>внутриартериальные методы реканализации</kwd><kwd>acute ischemic stroke</kwd><kwd>intraarterial methods of recanalization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Володюхин М.Ю., Хасанова Д.Р., Дёмин Т.В., и др., Внутриартериальная реперфузионная терапия у пациентов с острым ишемическим инсультом. Медицинский совет 2015; 10: 6-11</mixed-citation><mixed-citation xml:lang="en">Володюхин М.Ю., Хасанова Д.Р., Дёмин Т.В., и др., Внутриартериальная реперфузионная терапия у пациентов с острым ишемическим инсультом. Медицинский совет 2015; 10: 6-11</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Савелло А.В., Вознюк И.А., Свистов Д.В. Внутрисосудистое лечение ишемического инсульта в острейшем периоде (клинические рекомендации) - СПб. 2015</mixed-citation><mixed-citation xml:lang="en">Савелло А.В., Вознюк И.А., Свистов Д.В. Внутрисосудистое лечение ишемического инсульта в острейшем периоде (клинические рекомендации) - СПб. 2015</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Скворцова В.И., Шамалов Н.А., Анисимов К.В., и др., Результаты внедрения тромболитической терапии при ишемическом инсульте в Российской Федерации. Журнал неврологии и психиатрии им. С.С. Корсакова 2010; 12; 2: 17-22.</mixed-citation><mixed-citation xml:lang="en">Скворцова В.И., Шамалов Н.А., Анисимов К.В., и др., Результаты внедрения тромболитической терапии при ишемическом инсульте в Российской Федерации. Журнал неврологии и психиатрии им. С.С. Корсакова 2010; 12; 2: 17-22.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации ESC/EACTS по реваскуляризации миокарда 2014. Рабочая группа по реваскуляризации миокарда Европейского общества кардиологов (ESC) и Европейской ассоциации кардио-торакальных хирургов (EACTS). Российский кардиологический журнал 2015; 2: 5-81</mixed-citation><mixed-citation xml:lang="en">Рекомендации ESC/EACTS по реваскуляризации миокарда 2014. Рабочая группа по реваскуляризации миокарда Европейского общества кардиологов (ESC) и Европейской ассоциации кардио-торакальных хирургов (EACTS). Российский кардиологический журнал 2015; 2: 5-81</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Appireddy R., Demchuk A., Goyal M., Menon M., Eesa M., Choi Ph., Hill M. Endovascular therapy for ischemic stroke. J. Clin. Neurol, no. 11 (2015): 1-8.</mixed-citation><mixed-citation xml:lang="en">Appireddy R., Demchuk A., Goyal M., Menon M., Eesa M., Choi Ph., Hill M. Endovascular therapy for ischemic stroke. J. Clin. Neurol, no. 11 (2015): 1-8.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Broderick J., Palesch Y., Demchuk A., Yeatts S., Khatri P., Hill M., Jauch E., Jovin T., Yan B., Silver F., Kummer R., Molina C., Demaerschalk B., Budzik R., Clark W., Zaidat O., Malisch T., Goyal M., Schonewille W., Mazighi M., Engelter S., Anderson C., Spilker J., Carrozzella J., R.N., B.A., R.T.(R.), Karla J. Ryckborst, R.N., B.N., L. Scott Janis, Ph.D., Renйe H. Martin, Foster L., Tomsick T. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N. Engl. J. Med, no. 368 (2013): 893-903.</mixed-citation><mixed-citation xml:lang="en">Broderick J., Palesch Y., Demchuk A., Yeatts S., Khatri P., Hill M., Jauch E., Jovin T., Yan B., Silver F., Kummer R., Molina C., Demaerschalk B., Budzik R., Clark W., Zaidat O., Malisch T., Goyal M., Schonewille W., Mazighi M., Engelter S., Anderson C., Spilker J., Carrozzella J., R.N., B.A., R.T.(R.), Karla J. Ryckborst, R.N., B.N., L. Scott Janis, Ph.D., Renйe H. Martin, Foster L., Tomsick T. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N. Engl. J. Med, no. 368 (2013): 893-903.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Casaubon L.K., Boulanger J.M., Blacquiere D., Boucher S., Brown K., Goddard T., Gordon J., Horton M., Lalonde J., LaRiviere C., Lavoie P., Leslie P., McNeill J., Mennon B., Penn M., Perry J., Snieder E., Tymiansky D., Foley N., Smith E., Gubitz G., Hill M., Glasser E., Lindsay P. Canadian stroke best practice recommendations: hyperacute stroke care. Guidelines, update, no. 10 (2015): 924-994.</mixed-citation><mixed-citation xml:lang="en">Casaubon L.K., Boulanger J.M., Blacquiere D., Boucher S., Brown K., Goddard T., Gordon J., Horton M., Lalonde J., LaRiviere C., Lavoie P., Leslie P., McNeill J., Mennon B., Penn M., Perry J., Snieder E., Tymiansky D., Foley N., Smith E., Gubitz G., Hill M., Glasser E., Lindsay P. Canadian stroke best practice recommendations: hyperacute stroke care. Guidelines, update, no. 10 (2015): 924-994.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chimowitz M.I. Endovascular treatment for acute ischemic stroke-still unproven.N. Engl. J. Med, no. 368 (2013): 952- 955.</mixed-citation><mixed-citation xml:lang="en">Chimowitz M.I. Endovascular treatment for acute ischemic stroke-still unproven.N. Engl. J. Med, no. 368 (2013): 952- 955.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Gomis M., Dбvalos A. Recanalization and reperfusion therapies of acute ischemic stroke: what have we learned, what are the major research questions, and where are we headed? Frontiers in Neurology, no. 5 (2014): 226.</mixed-citation><mixed-citation xml:lang="en">Gomis M., Dбvalos A. Recanalization and reperfusion therapies of acute ischemic stroke: what have we learned, what are the major research questions, and where are we headed? Frontiers in Neurology, no. 5 (2014): 226.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Jayaraman M., Hussain S., Abruzzo T., Albani B., Albuquerque F., Alexander M., Ansari S., Arthur A., Baxter B., Bulsara K., Chen M., Delgado-Almandoz J., Fraser J., Heck D., Hetts S., Kelly M., Seon-Kyu Lee, Thabele Leslie-Mawzi, McTaggart R., Meyers Ph., Prestigiacomo Ch., Pride G., Patsalides A., Starke R., Tarr R., Frei D., Rasmussen P. Embolectomy for stroke with emergent large vessel occlusion (ELVO): report of the standards and guidelines committee of the society of neurointerventional surgery. J. Neuro. Intervent. Surg. no. 0 (2015): 1-6.</mixed-citation><mixed-citation xml:lang="en">Jayaraman M., Hussain S., Abruzzo T., Albani B., Albuquerque F., Alexander M., Ansari S., Arthur A., Baxter B., Bulsara K., Chen M., Delgado-Almandoz J., Fraser J., Heck D., Hetts S., Kelly M., Seon-Kyu Lee, Thabele Leslie-Mawzi, McTaggart R., Meyers Ph., Prestigiacomo Ch., Pride G., Patsalides A., Starke R., Tarr R., Frei D., Rasmussen P. Embolectomy for stroke with emergent large vessel occlusion (ELVO): report of the standards and guidelines committee of the society of neurointerventional surgery. J. Neuro. Intervent. Surg. no. 0 (2015): 1-6.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Khatri P., Yeatts S.D., Mazighi M., Broderick J., Liebeskind D., Demchuk A., Amarenco P., Carrozzella J., Spilker J., Foster L., Goyal M., Hill M., Palesch Y., Haley C., Vagal A., Tomsick T. Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the interventional management of stroke (IMS III) phase 3 trial. Lancet Neurol, no. 13 (2014): 567-574.</mixed-citation><mixed-citation xml:lang="en">Khatri P., Yeatts S.D., Mazighi M., Broderick J., Liebeskind D., Demchuk A., Amarenco P., Carrozzella J., Spilker J., Foster L., Goyal M., Hill M., Palesch Y., Haley C., Vagal A., Tomsick T. Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the interventional management of stroke (IMS III) phase 3 trial. Lancet Neurol, no. 13 (2014): 567-574.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kidwell C., Jahan R., Chelsea G., Kidwell S., Jahan R., Gornbein J., Alger J.,Nenov V., Ajani Z., Feng L., Meyer B., Olson S., Schwamm L., Yoo A., M.D., Randolph S. Marshall, Meyers Ph., Yavagal D., Wintermark M., Guzy J., Starkman S., Saver J. A Trial of imaging selection and endovascular treatment for ischemic stroke. Engl. J. Med, no. 368 (2013): 914-23.</mixed-citation><mixed-citation xml:lang="en">Kidwell C., Jahan R., Chelsea G., Kidwell S., Jahan R., Gornbein J., Alger J.,Nenov V., Ajani Z., Feng L., Meyer B., Olson S., Schwamm L., Yoo A., M.D., Randolph S. Marshall, Meyers Ph., Yavagal D., Wintermark M., Guzy J., Starkman S., Saver J. A Trial of imaging selection and endovascular treatment for ischemic stroke. Engl. J. Med, no. 368 (2013): 914-23.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">De Los Rноs la Rosa F., Khoury J., Kissela B., Flaherty M., Alwell K., Moomaw C., Khatri P., Adeoye O., Woo D., Ferioli S., Kleindorfer D. Eligibility for Intravenous recombinant tissue-type plasminogen activator within a population: the effect of the European cooperative acute stroke study (ECASS) III Trial. Stroke, no. 43 (2012): 1591- 1595.</mixed-citation><mixed-citation xml:lang="en">De Los Rноs la Rosa F., Khoury J., Kissela B., Flaherty M., Alwell K., Moomaw C., Khatri P., Adeoye O., Woo D., Ferioli S., Kleindorfer D. Eligibility for Intravenous recombinant tissue-type plasminogen activator within a population: the effect of the European cooperative acute stroke study (ECASS) III Trial. Stroke, no. 43 (2012): 1591- 1595.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Molina C.A. Futile recanalization in mechanical embolectomy trials: a call to improve selection of patients for revascularization. Stroke, no. 41 (2010): 842-843.</mixed-citation><mixed-citation xml:lang="en">Molina C.A. Futile recanalization in mechanical embolectomy trials: a call to improve selection of patients for revascularization. Stroke, no. 41 (2010): 842-843.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Chia N., Leyden J., Newbury J., Jannes J., Kleinig T. Determiningthe numberof ischemic strokes potentially eligiblefor endovascular thrombectomy: a population based study. Stroke, no. 47 (2016): 1377-1380.</mixed-citation><mixed-citation xml:lang="en">Chia N., Leyden J., Newbury J., Jannes J., Kleinig T. Determiningthe numberof ischemic strokes potentially eligiblefor endovascular thrombectomy: a population based study. Stroke, no. 47 (2016): 1377-1380.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta N., Jovin T., Levy E., Levy E., Liebeskind D., Zaidat O., Rai A., Hirsch J., Hsu D., Rymer M., Tayal A., Lin R., Natarajan S., Nanda A., Tian M., Hao Q., Kalia J., Chen M., Abou-Chebl A., Nguyen Th., Yoo A. Predictors and clinical relevance of hemorrhagic transformation after endovascular therapy for anterior circulation large vessel occlusion strokes: a multicenter retrospective analysis of 1122 patients. NeuroIntervent. Surg, no. 7 (2015): 16-21.</mixed-citation><mixed-citation xml:lang="en">Gupta N., Jovin T., Levy E., Levy E., Liebeskind D., Zaidat O., Rai A., Hirsch J., Hsu D., Rymer M., Tayal A., Lin R., Natarajan S., Nanda A., Tian M., Hao Q., Kalia J., Chen M., Abou-Chebl A., Nguyen Th., Yoo A. Predictors and clinical relevance of hemorrhagic transformation after endovascular therapy for anterior circulation large vessel occlusion strokes: a multicenter retrospective analysis of 1122 patients. NeuroIntervent. Surg, no. 7 (2015): 16-21.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Powers W., Derdeyn C., Biller J., Coffey C., Hoh B., Jauch E., Johnston K., Johnston S., Khalessi A., Kidwell C., Meschia J., Ovbiagele B., Yavagal D. Guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: a guideline for healthcare professionals from the American Heart Association // American Stroke Association. Stroke. 46 (2015) : 3020-3035. doi: 10.1161/STR.0000000000000074.</mixed-citation><mixed-citation xml:lang="en">Powers W., Derdeyn C., Biller J., Coffey C., Hoh B., Jauch E., Johnston K., Johnston S., Khalessi A., Kidwell C., Meschia J., Ovbiagele B., Yavagal D. Guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: a guideline for healthcare professionals from the American Heart Association // American Stroke Association. Stroke. 46 (2015) : 3020-3035. doi: 10.1161/STR.0000000000000074.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rai A. Red pill, blue pill: reflection son the emerging large vessel stroke ‘market’. J. Neuro. Intervent. Surg, no. 7 (2015): 623-625.</mixed-citation><mixed-citation xml:lang="en">Rai A. Red pill, blue pill: reflection son the emerging large vessel stroke ‘market’. J. Neuro. Intervent. Surg, no. 7 (2015): 623-625.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Raychev R., Jahan R., Liebeskind D., Clark W., Nogueira R.G., Saver J. Determinants of intracranial hemorrhage occurrence and outcome after neurothrombectomy therapy: insights from the Solitaire FR with intention for thrombectomy randomized trial. Am. J. Neuroradiol, no. 36 (2015): 2303- 2307.</mixed-citation><mixed-citation xml:lang="en">Raychev R., Jahan R., Liebeskind D., Clark W., Nogueira R.G., Saver J. Determinants of intracranial hemorrhage occurrence and outcome after neurothrombectomy therapy: insights from the Solitaire FR with intention for thrombectomy randomized trial. Am. J. Neuroradiol, no. 36 (2015): 2303- 2307.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Riedel C., Zimmermann P., Jensen-Kondering U., Stingele R., Deuschl G., Jansen O. The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke, no. 42 (2011): 1775-177.</mixed-citation><mixed-citation xml:lang="en">Riedel C., Zimmermann P., Jensen-Kondering U., Stingele R., Deuschl G., Jansen O. The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke, no. 42 (2011): 1775-177.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Shams T., Zaidat O., Yavagal D., Xavier A., Jovin T., Janardhan V. Society of Vascular and Interventional Neurology (SVIN) Stroke Interventional Laboratory Consensus (SILC) Criteria: A 7M Management Approach to Developing a Stroke Interventional Laboratory in the Era of Stroke Thrombectomy for Large Vessel Occlusions. Intervent. Neurol, no. 5 (2016): 1-28.</mixed-citation><mixed-citation xml:lang="en">Shams T., Zaidat O., Yavagal D., Xavier A., Jovin T., Janardhan V. Society of Vascular and Interventional Neurology (SVIN) Stroke Interventional Laboratory Consensus (SILC) Criteria: A 7M Management Approach to Developing a Stroke Interventional Laboratory in the Era of Stroke Thrombectomy for Large Vessel Occlusions. Intervent. Neurol, no. 5 (2016): 1-28.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Training guidelines for endovascular ischemic stroke intervention: an international multi society consensus document. The e-Journal of the European society of minimally invasive neurological therapy, no. 18 (2016): 0 - 7.</mixed-citation><mixed-citation xml:lang="en">Training guidelines for endovascular ischemic stroke intervention: an international multi society consensus document. The e-Journal of the European society of minimally invasive neurological therapy, no. 18 (2016): 0 - 7.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y., Liao X., Zhao X., Wang D., Wang C., Nguyen-Huynh M., Zhou Y., Liu L., Wang X., Liu G., Li H., Wang Y. Using recombinant tissue plasminogen activator to treat acute ischemic stroke in china: Analysis of the results from the Chinese National Stroke Registry (CNSR). Stroke, no. 42 (2011): 1658-1664.</mixed-citation><mixed-citation xml:lang="en">Wang Y., Liao X., Zhao X., Wang D., Wang C., Nguyen-Huynh M., Zhou Y., Liu L., Wang X., Liu G., Li H., Wang Y. Using recombinant tissue plasminogen activator to treat acute ischemic stroke in china: Analysis of the results from the Chinese National Stroke Registry (CNSR). Stroke, no. 42 (2011): 1658-1664.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
