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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/1683-3295-2016-0-1-28-34</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-346</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ РАБОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>ЭНДОВАСКУЛЯРНЫЕ МЕТОДЫ ВОССТАНОВЛЕНИЯ КРОВОТОКА ПРИ ТРОМБОЗЕ ВНУТРЕННЕЙ СОННОЙ АРТЕРИИ У ПАЦИЕНТОВ В ОСТРЕЙШЕЙ ФАЗЕ ИШЕМИЧЕСКОГО ИНСУЛЬТА</article-title><trans-title-group xml:lang="en"><trans-title>ENDOVASCULAR TECHNIQUES FOR BLOOD FLOW RESTORATION IN CASE OF THROMBOSIS OF INTERNAL CAROTID ARTERY IN PATIENTS WITH ACUTE ISCHEMIC STROKE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Володюхин</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Volodyukhin</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Володюхин Михаил Юрьевич — кандидат медедицинских наук, зав. отделением РХМДЛ ГАУЗ МКДЦ. </p><p>420116 Россия, г. Казань, ул. Карбышева, 12а.</p></bio><email xlink:type="simple">voloduckin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хасанова</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khasanova</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хасанова Дина Рустемовна — доктор медицинских наук, проффессор, главный внештатный невролог МЗ РТ. </p><p>420116 Россия, г. Казань, ул. Карбышева, 12а.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демин</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Demin</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Демин Тимур Викторович — зав. отделением острого инсульта ГАУЗ МКДЦ.</p><p>420116 Россия, г. Казань, ул. Карбышева, 12а.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГАУЗ «Межрегиональный клинико-диагностический центр».</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>06</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>28</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Володюхин М.Ю., Хасанова Д.Р., Демин Т.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Володюхин М.Ю., Хасанова Д.Р., Демин Т.В.</copyright-holder><copyright-holder xml:lang="en">Volodyukhin M.Y., Khasanova D.R., Demin T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/346">https://www.therjn.com/jour/article/view/346</self-uri><abstract><p>ель. В данной работе представлен опыт применения внутриартериальных методов восстановления кровотока у пациентов с острым ишемическим инсультом на фоне тромбоза внутренней сонной артерии (ВСА). Материалы и методы. Эндоваскулярная реваскуляризация была выполнена 11 пациентам — 8 мужчинам и 3 женщинам. Средний возраст больных составил 62 года. Неврологический дефицит при поступлении варьировал от 15 до 24 баллов по шкале NIHSS ( в среднем составил 18 баллов). Внутриартериальная тромболитическая терапия (ВА ТЛТ) была проведена 2 пациентам, стентирование экстракраниального сегмента ВСА — 7 больным. Двум пациентам реваскуляризация выполнена путем селективной катетеризацией средней мозговой артерии (СМА) из контралатеральной ВСА через систему передней соединительной артерии. Двум пациентам реваскуляризация выполнена путем тромбэкстракции из СМА через окклюзированный сегмент ВСА на фоне временной окклюзии общей сонной артерии. Результаты. Полного восстановления кровотока по интракраниальным артериям (TICI 2b-3) удалось достичь у 5 (45,4%) пациентов, частичную реканализацию (TICI 2a) наблюдали у 2 пациентов, у остальных больных восстановить кровоток не удалось. Симптомные кровоизлияния (паренхиматозная гематома 2-го типа) наблюдали у 2 пациентов, в одном наблюдении развился фатальный отек головного мозга. Благоприятный клинический исход, оцениваемый по шкале Рэнкина (0—2 балла) на 30-е сутки, наблюдали у 2 пациентов. Летальность составила 27,2% (умерли 3 пациента). Заключение. Для безопасного и эффективного выполнения внутриартериальной реперфузионной терапии у пациентов с острым тромбозом ВСА необходим тщательный отбор пациентов с оценкой объема ишемического повреждения головного мозга. При остром тромбозе ВСА следует применять только механические средства реваскуляризации. При выборе типа вмешательства следует учитывать тип окклюзии ВСА и степень развития коллатерального кровотока.</p></abstract><trans-abstract xml:lang="en"><p>Objective: To present the results of intraarterial methods applying for blood flow restoration (recanalization) in case of thrombosis of internal carotid artery (ICA) in patients with acute ischemic stroke (ACI) Materials and Methods: During period from December 2006 till February 2014, 11 patients (8 men, 3 women), average aged 62, with ACI symptoms and occlusion of ICA were treated within 6-hour therapeutic window using various methods of intraarterial recanalization. The average severity of neurological deficit at admission was 18 scores by NIHSS. Two patients were treated with selective infusion of the rt-PA (Actilyse «Boehringer Ingelheim») thrombolytic agent and aspiration of thrombotic masses, while ICA stenting was performed in 7 patients. Stent-assisting devices with the Solitaire stent (EV3) were used in 4 patients. Results: The successful recanalization of (TICI 2b-3) ICA was achieved in 45,7%. The frequency of symptomatic hemorrhagic transformations in patients with ICA occlusion was 18,3% while the fatal brain edema was observed in one case. The good clinical (neurological impairment — 0-2 scores by mRs) outcome was observed in 2 patients, mortality was 27,2% (3 patient died). Conclusions: The accurate selection of patients with evaluation of the volume of brain ischemic damage is necessary for safe and effective intraarterial reperfusion in case of acute ICA thrombosis. The mechanical devices of revascularization should only be used in case of acute ICA thrombosis. The type of ICA occlusion and degree of collateral blood flow must be taking into account during selection of surgical intervention type</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбоз</kwd><kwd>ишемический инсульт</kwd><kwd>эндоваскулярные методы восстановления кровотока</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ICA thrombosis</kwd><kwd>ischemic stroke</kwd><kwd>endovascular methods for blood flow restoration</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Володюхин М.Ю., Хасанова Д.Р., Демин Т.В., и др. Влияние объема очага ишемии на результат применения интервенционных методов лечения острого ишемического инсульта-первые результаты // «Медицинская визуализация». — 2010. — №4. — С. 89 — 90.</mixed-citation><mixed-citation xml:lang="en">Володюхин М.Ю., Хасанова Д.Р., Демин Т.В., и др. 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