neurosurgeryНейрохирургияRussian journal of neurosurgery1683-32952587-7569Издательский дом "МедИНК"10.63769/1683-3295-2016-0-2-73-78neurosurgery-292Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWМЕТОД КОРТИКО-КОРТИКАЛЬНЫХ ВЫЗВАННЫХ ПОТЕНЦИАЛОВ В НЕЙРОХИРУРГИЧЕСКОЙ ПРАКТИКЕThe method of corticocortical evoked potentials in neurosurgical practiceЧищинаНина ВладимировнаChishchinaNina Vladimirovnanina_chishchina@mail.ru. n_chischina@neuronsk.ruРзаевДжамиль АфетовичRzaevJamil Afetovichd_rzaev@neuronsk.ruМойсакГалина ИвановнаMoisakGalina Ivanovnag_moisak@neuronsk.ruФГБУ «Федеральный центр нейрохирургии»Russian FederationНовосибирский Государственный Университет ; ФГБУ «Федеральный центр нейрохирургии»Russian Federation201605102017027378Copyright © Чищина Н.В., Рзаев Д.А., Мойсак Г.И., 20172017Чищина Н.В., Рзаев Д.А., Мойсак Г.И.Chishchina N.V., Rzaev J.A., Moisak G.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therjn.com/jour/article/view/292

Цель: Обзор литературы о клинических исследованях, в которых применялся метод кортико-кортикальных вызванных потенциалов (ККВП) в рамках нейрохирургической практики. Материалы и методы. Проведен анализ 38 публикаций международной базы данных Pubmed в которых использован метод регистрации ККВП у пациентов с нейрохирургической патологией. Работы были опубликованы с 1970 г. до июля 2014 г. Результаты. Метод ККВП позволяет получить информацию о наличии нейрональных связей между функциональными зонами коры головного мозга, идентифицировать направление межнейрональных связей (определить зоны, принимающие или генерирующие сигналы), определить степень возбудимости коры в области эпилептического очага и вокруг него и получить информацию о путях распространения эпилептической активности по коре и подкорковым структурам головного мозга. Заключение: ККВП являются перспективным методом для изучения взаимосвязей между различными корковыми и подкорковыми структурами головного мозга у нейрохирургических пациентов во время операции, а также до и после вмешательства. Этот метод может быть использован в условиях как местной (во время хирургии с пробуждением), так и общей анестезии.

Objective: to perform the literature review of clinical trials data examined the method of cortico-cortical evoked potentials (CCEP) in neurosurgical practice. Material and methods. The analysis of 38 reports from international database Pubmed, which presented the CCEP method in patients suffered from neurosurgical pathology (publication dates from 1970 till July 2014). Results. CCEP method allows receiving information concerning existence of neuronal connections between functional cortical areas, identifying the direction of interneurinal connections (to determing receiving or generating zones) and evaluating the degree of cortical excitability in the area of epilepric zone and in surrounding tissues as well as getting information about seizure pattern paths along the cortex and subcortical structures. Conclusion: CCEP is a perspective method for investigation of connections between various cortical and subcortical structures in patients with neurosurgical pathology in pre- and postoperative periods as well as intraoperatively. This method can be useful in conditions of local (during awake surgery) and general anaesthesia.

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The authors declare that there are no conflicts of interest present.