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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/1683-3295-2015-0-2-86-91</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-170</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ПОДХОДЫ К ЛУЧЕВОЙ ТЕРАПИИ МЕТАСТАТИЧЕСКОГО ПОРАЖЕНИЯ ГОЛОВНОГО МОЗГА</article-title><trans-title-group xml:lang="en"><trans-title>The modern approaches to radiotherapy of brain metastatic lesions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зинькович</surname><given-names>Михаил Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zin’Kovich</surname><given-names>M. S.</given-names></name></name-alternatives><email xlink:type="simple">onco_doc@pochta.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Розенко</surname><given-names>Людмила Яковлевна</given-names></name><name name-style="western" xml:lang="en"><surname>Rozenko</surname><given-names>L. Ya.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусарева</surname><given-names>Марина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Gusareva</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">oncorad@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балязин-Парфенов</surname><given-names>Игорь Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Balyazin-Parfenov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">balyazinparfenov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Ростовский научно-исследовательский онкологический институт</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>86</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зинькович М.С., Розенко Л.Я., Гусарева М.А., Балязин-Парфенов И.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Зинькович М.С., Розенко Л.Я., Гусарева М.А., Балязин-Парфенов И.В.</copyright-holder><copyright-holder xml:lang="en">Zin’Kovich M.S., Rozenko L.Y., Gusareva M.A., Balyazin-Parfenov I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/170">https://www.therjn.com/jour/article/view/170</self-uri><abstract><p>Несмотря на высокий уровень современной доказательной медицины, продолжаются споры о методах и тактике лечения метастатического поражения головного мозга. Быстро увеличивающаяся доказательная база демонстрирует, что радиотерапия обеспечивает эффективный и предсказуемый локальный контроль над опухолью, позволяет продлить продолжительность жизни, а также уменьшить вероятность развития новых метастатических очагов. Комплексный подход с сочетанием облучения всего головного мозга с методиками локального воздействия обладает наибольшим лечебным потенциалом и позволяет добиться лучших результатов.</p></abstract><trans-abstract xml:lang="en"><p>The discussions concerning methods and strategy treatment for brain metastatic lesions are still conducting in spite of high level of current evidence-based healthcare. The rapidly growing evidence database demonstrates that radiotherapy provides effective and predictive local control over tumor lesions as well as allows extanding the patient’s lifetime and decreasing the probability of new metastatic lesions development. The complex approach including combination of whole brain radiotherapy and various methods of local treatment has the most therapeutic capacity and allows achieving the best treatment outcomes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>внутримозговые метастазы</kwd><kwd>радиотерапия</kwd><kwd>облучение всего головного мозга</kwd><kwd>стереотаксическая радиохирургия</kwd><kwd>brain metastases</kwd><kwd>radiotherapy</kwd><kwd>whole brain radiotherapy</kwd><kwd>stereotactic radiosurgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Григоров С.В. Ростов-на-Дону. 2008 г. Докторская диссертация: Новые подходы в комплексном лечении первичных злокачественных и метастатических опухолей центральной нервной системы.</mixed-citation><mixed-citation xml:lang="en">Григоров С.В. Ростов-на-Дону. 2008 г. 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