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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.63769/1683-3295-2025-27-2-70-75</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-1685</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ РАБОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>Использование резервуара Оммайа в комплексном лечении пациентов с метастатическим поражением головного мозга: показания, эффективность, перспективы</article-title><trans-title-group xml:lang="en"><trans-title>Ommaya reservoir in complex treatment of patients with brain metastases: Indications, efficacy, prospects</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1389-9038</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алешин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleshin</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Александрович Алешин</p><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>Vladimir Aleksandrovich Aleshin </p><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><email xlink:type="simple">aloshin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4744-6141</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кононец</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kononets</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4160-9598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекяшев</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekyashev</surname><given-names>A. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1766-0032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4218-9652</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насхлеташвили</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Naskhletashvili</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0194-7645</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаспарян</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gasparyan</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5841-7480</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Севян</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sevyan</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4125-7342</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрофанов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitrofanov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8880-1758</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прозоренко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prozorenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><bio xml:lang="en"><p>24 Kashirskoye Hwy., Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4031-0540</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суфианов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sufianov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5242-9309</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москвина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskvina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6325-716X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карахан</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakhan</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115478 Москва, Каширское ш., 23</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Oncology named after N. N. Blokhin of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>08</month><year>2025</year></pub-date><volume>27</volume><issue>2</issue><fpage>70</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алешин В.А., Кононец П.В., Бекяшев А.Х., Белов Д.М., Насхлеташвили Д.Р., Гаспарян Т.Г., Севян Н.В., Митрофанов А.А., Прозоренко Е.В., Суфианов Р.А., Москвина Е.А., Карахан В.Б., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Алешин В.А., Кононец П.В., Бекяшев А.Х., Белов Д.М., Насхлеташвили Д.Р., Гаспарян Т.Г., Севян Н.В., Митрофанов А.А., Прозоренко Е.В., Суфианов Р.А., Москвина Е.А., Карахан В.Б.</copyright-holder><copyright-holder xml:lang="en">Aleshin V.A., Kononets P.V., Bekyashev A.K., Belov D.M., Naskhletashvili D.R., Gasparyan T.G., Sevyan N.V., Mitrofanov A.A., Prozorenko E.V., Sufianov R.A., Moskvina E.A., Karakhan V.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/1685">https://www.therjn.com/jour/article/view/1685</self-uri><abstract><sec><title>Введение</title><p>Введение. Хирургическая тактика лечения пациентов с церебральными метастазами с выраженным кистозным компонентом неоднозначна ввиду сложности резекции таких опухолей с соблюдением принципов абластичности.</p><p>Цель работы – представить методику лечения пациентов с метастатическим поражением головного мозга с выраженным кистозным компонентом, включающую малоинвазивное нейрохирургическое вмешательство: имплантацию хронической субкутанной дренирующей системы – резервуара Оммайа.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В Национальном медицинском исследовательском центре онкологии им. Н. Н. Блохина Минздрава России за период с 2007 по 2022 г. имплантация резервуара Оммайа проведена 100 пациентам с различными формами опухолевого поражения центральной нервной системы с выраженным кистозным компонентом.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Использование методики имплантации хронической субкутанной дренирующей системы (резервуара Оммайа) в комплексном лечении пациентов с метастатическим поражением головного мозга позволило в большинстве случаев добиться контроля размеров кистозного компонента опухоли с последующим проведением локального лучевого воздействия. Прямое нейрохирургическое вмешательство в объеме резекции опухоли при новообразованиях с выраженным кистозным компонентом – в отличие от предлагаемой методики – обычно не соответствует онкологическому принципу абластичности ввиду фрагментации патологической ткани и приводит к быстрому локальному рецидиву и диссеминации.</p></sec><sec><title>Заключение</title><p>Заключение. Хирургическое лечение пациентов с нейроонкологической патологией вторичного характера – непростая проблема, связанная с необходимостью сочетать адекватные нейрохирургические и онкологические подходы и тактики лечения. Сочетание функциональной доступности (нейрохирургический аспект) и абластичности (онкологический аспект) не всегда может быть достигнуто в адекватном объеме. Применение резервуара Оммайа в комплексном лечении пациентов с метастатическим поражением головного мозга с выраженным кистозным компонентом показало свою эффективность и должно использоваться в рутинной практике нейрохирурга, занимающегося нейроонкологической патологией.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Surgical tactics in treatment of patients with brain metastases and significant cystic component are ambiguous due to the complexity of resection of such tumors in compliance with the principles of thorough oncological treatment.</p></sec><sec><title>Aim</title><p>Aim. Presentation of a method for treatment of patients with metastatic lesions in the brain with a large cystic component using minimally invasive neurosurgical intervention: implantation of a chronic subcutaneous drainage system – the Ommaya reservoir.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. At the National Medical Research Center of Oncology named after N. N. Blokhin of the Ministry of Health of the Russian Federation, from 2007 to 2022, Ommaya reservoir implantation was performed in 100 patients with various forms of tumors of the central nervous system and significant cystic component.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The use of the technique of implantation of a constant subcutaneous drainage system – the Ommaya reservoir – in complex treatment of patients with brain metastases in most cases allowed to control the size of the cystic component of the tumor with subsequent local radiation exposure. Direct neurosurgical intervention in the form of tumor resection usually does not comply with the principle of thorough oncological treatment of neoplasms with a significant cystic component due to fragmentation of pathological tissue that leads to rapid local recurrence and dissemination.</p></sec><sec><title>Conclusion</title><p>Conclusion. Surgical treatment of patients with brain metastases is a difficult problem due to the need for a combination of adequate neurosurgical and oncological approaches and tactics. Functional accessibility (neurosurgery) and thoroughness (oncology) cannot always be achieved together to an adequate extent. The use of the Ommaya reservoir in complex treatment of patients with brain metastases with a large cystic component has shown its effectiveness and should be used in the routine practice of a neurosurgeon.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>метастаз в головной мозг</kwd><kwd>резервуар Оммайа</kwd><kwd>нейроонкология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brain metastasis</kwd><kwd>Ommaya reservoir</kwd><kwd>neuro-oncology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yamanaka Y., Shuto T., Kato Y. et al. Ommaya reservoir placement followed by Gamma Knife surgery for large cystic metastatic brain tumors. J Neurosurg 2006;(105 Suppl):79–81. DOI: 10.3171/sup.2006.105.7.79</mixed-citation><mixed-citation xml:lang="en">Yamanaka Y., Shuto T., Kato Y. et al. 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