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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/1683-3295-2024-26-4-22-27</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-1604</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ РАБОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>Предоперационная эмболизация с использованием системы Onyx при внутричерепных артериовенозных мальформациях: ранний одноцентровой опыт</article-title><trans-title-group xml:lang="en"><trans-title>Preoperative Onyx embolization of intracranial arteriovenous malformations: a single center early experience</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Elsherbini</surname><given-names>M. M.</given-names></name><name name-style="western" xml:lang="en"><surname>Elsherbini</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><bio xml:lang="en"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><email xlink:type="simple">m_elsherbiny@mans.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Nabeeh</surname><given-names>M. M.</given-names></name><name name-style="western" xml:lang="en"><surname>Nabeeh</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><bio xml:lang="en"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Kassem</surname><given-names>M. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Kassem</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><bio xml:lang="en"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ezz Eldin</surname><given-names>A.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezz Eldin</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><bio xml:lang="en"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Farouk</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Farouk</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><bio xml:lang="en"><p>Faculty of Medicine; Neurosurgery Department</p><p>Mansoura</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Mansoura University</institution><country>Египет</country></aff><aff xml:lang="en"><institution>Mansoura University</institution><country>Egypt</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>23</day><month>01</month><year>2025</year></pub-date><volume>26</volume><issue>4</issue><fpage>22</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Elsherbini M.M., Nabeeh M.M., Kassem M.A., Ezz Eldin A., Farouk M., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Elsherbini M.M., Nabeeh M.M., Kassem M.A., Ezz Eldin A., Farouk M.</copyright-holder><copyright-holder xml:lang="en">Elsherbini M.M., Nabeeh M.M., Kassem M.A., Ezz Eldin A., Farouk M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/1604">https://www.therjn.com/jour/article/view/1604</self-uri><abstract><sec><title>   Введение</title><p>   Введение. Внутричерепные артериовенозные мальформации (АВМ) – угрожающие жизни, сложные для лечения патологии. Эндоваскулярная эмболизация внутричерепных АВМ была разработана в последние 2 десятилетия для cнижения степени тяжести мальформации, что предположительно приводит к более благоприятным исходам хирургического лечения.</p></sec><sec><title>   Пациенты и методы</title><p>   Пациенты и методы. Проведен ретроспективный анализ данных всех пациентов, которым был поставлен диагноз АВМ головного мозга в больницах университета Мансура в период с января 2017 г. по декабрь 2022 г. Изучены клинические и радиологические исходы, а также степень удовлетворенности хирурга и сложности в ходе процедуры.</p></sec><sec><title>   Результаты</title><p>   Результаты. Девять пациентов соответствовали критериям мультимодального лечения, в том числе 7 женщин. Средний возраст пациентов составил 36 лет. У всех пациентов сумма баллов по модифицированной шкале Рэнкина после эмболизации не изменилась. У 1 пациента после операции развился дополнительный неврологический дефицит в форме усиления двигательного дефицита, который вернулся на исходный уровень в период наблюдения. Средняя продолжительность наблюдения составила 103 дня.</p></sec><sec><title>   Заключение</title><p>   Заключение. Предоперационная эмболизация – безопасный метод, характеризующийся благоприятными исходами и выполнимой хирургической методикой, который следует использовать как часть мультимодального лечения тяжелых АВМ головного мозга.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>   Introduction</title><p>   Introduction. Intracranial arteriovenous malformations (AVM) are considered one of the life-threatening pathologies which are challenging to manage. Endovascular embolization of intracranial AVMs is a line of management which developed over the past two decades to downgrade the lesion, a step is thought to make surgeries of more favorable outcome.</p></sec><sec><title>   Patients and methods</title><p>   Patients and methods. All patients who were diagnosed with brain AVM in Mansoura University Hospitals between January 2017 through December 2022 were retrospectively analyzed. Clinical and radiological outcome were studied, as well as surgeons’ satisfaction and procedural difficulties.</p></sec><sec><title>   Results</title><p>   Results. Nine patients met the criteria for multimodal management, seven of them were female, mean age of the group 36 years. Patients’ mRS remained unchanged after embolization sessions, one patient had an added neurological deficit in the form of increased severity of motor deficit after surgery, which was reversible during follow up period, mean follow up period is 103 days.</p></sec><sec><title>   Conclusion</title><p>   Conclusion. Pre-operative embolization is a safe tool to be added to the muti-modal treatment of high grades cerebral AVM’s with good outcome and feasible surgical technique.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>внутричерепные артериовенозные мальформации</kwd><kwd>мультимодальное лечение</kwd><kwd>гибридные методы</kwd><kwd>эмболизация Onyx</kwd><kwd>предоперационная эмболизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>intracranial arteriovenous malformations</kwd><kwd>muti-modal treatment</kwd><kwd>hybrid techniques</kwd><kwd>Onyx embolization</kwd><kwd>preoperative embolization</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена без спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The work was performed without external funding</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Spetzler R.F., Martin N.A. 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