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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/1683-3295-2023-25-2-140-147</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-1382</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Транскраниальный фокусированный ультразвук в нейрохирургии: терапевтические возможности и экспериментальные исследования</article-title><trans-title-group xml:lang="en"><trans-title>Transcranial focused ultrasound in neurosurgery: therapeutic possibilities and experimental studies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2815-280X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvortsova</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997 Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>Bld. 10, 1 Ostrovytianova St., Moscow 117342</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6637-8098</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997 Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>Bld. 10, 1 Ostrovytianova St., Moscow 117342</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5337-8715</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джафаров</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhafarov</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виджай Маисович Джафаров</p><p>117997 Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>Vidzhai Maisovich Dzhafarov</p><p>Bld. 10, 1 Ostrovytianova St., Moscow 117342</p></bio><email xlink:type="simple">vidzhaid@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5743-8279</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сенько</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Senko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997 Москва, ул. Островитянова, 1, стр. 10</p></bio><bio xml:lang="en"><p>Bld. 10, 1 Ostrovytianova St., Moscow 117342</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5256-0905</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крылов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krylov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117997 Москва, ул. Островитянова, 1, стр. 10; 117997 Москва, ул. Островитянова, 1; 129090 Москва, Б. Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Bld. 10, 1 Ostrovytianova St., Moscow 117342; 1 Ostrovityanova St., Moscow 117997; 3 Bolshaya Sukharevskaya Sq., Moscow 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр мозга и нейротехнологий» ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Brain Research and Neurotechnology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр мозга и нейротехнологий» ФМБА России; ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пирогова» Минздрава России; ГБУЗ «НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения города Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Brain Research and Neurotechnology; N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>11</day><month>07</month><year>2023</year></pub-date><volume>25</volume><issue>2</issue><fpage>140</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Скворцова В.И., Белоусов В.В., Джафаров В.М., Сенько И.В., Крылов В.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Скворцова В.И., Белоусов В.В., Джафаров В.М., Сенько И.В., Крылов В.В.</copyright-holder><copyright-holder xml:lang="en">Skvortsova V.I., Belousov V.V., Dzhafarov V.M., Senko I.V., Krylov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/1382">https://www.therjn.com/jour/article/view/1382</self-uri><abstract><sec><title>Введение</title><p>Введение. Современным технологиям удалось обойти костный барьер с помощью ультразвуковых волн, и арсенал нейрохирургических инструментов пополнился транскраниальным фокусированным ультразвуком (ФУЗ). Сочетание этого метода с магнитно‑резонансной томографией (МРТ) позволяет выполнять операции под непосредственным контролем расположения очага деструкции и степени ее выраженности во время процедуры.</p><p>Цель работы – представить обзор литературы по современному применению метода ФУЗ‑МРТ в нейрохирургии. На протяжении десятилетий ультразвук (УЗ) в медицине используется преимущественно в диагностических целях. Современные технологии привели к появлению возможности применять УЗ в нейрохирургии с лечебной целью без открытого вмешательства. Сегодня транскраниальный ФУЗ‑МРТ – инновация в медицине, расширяющая горизонты малоинвазивной хирургии. Проведенные исследования применения метода ФУЗ доказывают эффективное лечение тремора и ряда других патологий, а многие научные проекты представляют собой перспективные направления.</p></sec><sec><title>Заключение</title><p>Заключение. Применение метода ФУЗ‑МРТ открывает широкие перспективы.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Since modern technologies have managed to bypass the bone barrier for ultrasound waves, the arsenal of neurosurgical instruments has been replenished with transcranial focused ultrasound (FUS). The combination of this method with magnetic resonance imaging (MRI) allows you to perform operations under the direct control of the location of the focus of destruction and the degree of its severity during the procedure.</p></sec><sec><title>Aim</title><p>Aim. To present a review of the literature on the modern application of the focused ultrasound under MRI control (MRgFUS) method in neurosurgery. Ultrasound has been used in medicine mainly for diagnostic purposes for decades. Modern technologies have led to the possibility of using ultrasound in neurosurgery for therapeutic purposes without open intervention. Today transcranial MRgFUS is an innovation in medicine, expanding the horizons of minimally invasive surgery. The conducted studies of the focused ultrasound method prove the effective treatment of tremor and a number of other pathologies, and many scientific projects represent promising areas.</p></sec><sec><title>Conclusion</title><p>Conclusion. The use of the MRgFUS method opens up broad prospects.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>фокусированный ультразвук</kwd><kwd>тремор</kwd><kwd>болезнь Паркинсона</kwd><kwd>эссенциальный тремор</kwd><kwd>ультразвук</kwd><kwd>магнитно‑резонансная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>focused ultrasound</kwd><kwd>tremor</kwd><kwd>Parkinson’s disease</kwd><kwd>essential tremor</kwd><kwd>ultrasound</kwd><kwd>magnetic resonance imaging</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lindtsrom P. Prefrontal ultrasonic irradiation – a substitute for lobotomy. Arch Neurol Psychiatry 1954;72(4):399. DOI: 10.1001/archneurpsyc.1954.02330040001001</mixed-citation><mixed-citation xml:lang="en">Lindtsrom P. Prefrontal ultrasonic irradiation – a substitute for lobotomy. Arch Neurol Psychiatry 1954;72(4):399. 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