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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurosurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Нейрохирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of neurosurgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3295</issn><issn pub-type="epub">2587-7569</issn><publisher><publisher-name>Издательский дом "МедИНК"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17650/1683-3295-2021-23-2-25-33</article-id><article-id custom-type="elpub" pub-id-type="custom">neurosurgery-1029</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ РАБОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group></article-categories><title-group><article-title>Отдаленные клинико-рентгенологические исходы тотальной артропластики межпозвонковых дисков на уровне пояснично-крестцового перехода</article-title><trans-title-group xml:lang="en"><trans-title>Long-term clinical and radiological outcomes after total lumbar disc replacement at the lumbosacral junction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9039-9147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иван Андреевич Степанов</p><p>664003 Иркутск, ул. Красного Восстания, 1; 664025 Иркутск, ул. Горького, 8</p></bio><bio xml:lang="en"><p>Ivan Andreevich Stepanov</p><p>1 Krasnogo Vosstaniya St., Irkutsk 664003; 8Gorkogo St., Irkutsk 664025</p></bio><email xlink:type="simple">stepanovivanneuro@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3299-1924</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белобородов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Beloborodov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003 Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>1 Krasnogo Vosstaniya St., Irkutsk 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саакян</surname><given-names>З. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Saakyan</surname><given-names>Z. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>677005 Якутск, ул. П. Алексеева, 83а</p></bio><bio xml:lang="en"><p>83a P. Alekseeva St., Yakutsk 677005</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Томашов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tomashov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>672038 Чита, ул. Коханского, 7</p></bio><bio xml:lang="en"><p>Kokhanskogo St., 7, Chita 672038</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трепезников</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Trepeznikov</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>353915 Новороссийск, ул. Революции 1905 года, 30</p></bio><bio xml:lang="en"><p>30 Revolutsii 1905goda St., Novorossiysk 353915</p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Иркутский государственный медицинский университет Минздрава России; Харлампиевская клиника, ООО</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical University; Kharlampiev Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО Иркутский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ РС(Я) Республиканская больница № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Hospital № 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГУЗ Краевая клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ Городская клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>10</day><month>06</month><year>2021</year></pub-date><volume>23</volume><issue>2</issue><fpage>25</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Степанов И.А., Белобородов В.А., Саакян З.С., Томашов И.И., Трепезников В.Г., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Степанов И.А., Белобородов В.А., Саакян З.С., Томашов И.И., Трепезников В.Г.</copyright-holder><copyright-holder xml:lang="en">Stepanov I.A., Beloborodov V.A., Saakyan Z.S., Tomashov I.I., Trepeznikov V.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therjn.com/jour/article/view/1029">https://www.therjn.com/jour/article/view/1029</self-uri><abstract><p>Цель исследования - провести анализ отдаленных клинико-рентгенологических исходов тотальной артропластики межпозвонковых дисков на уровне пояснично-крестцового перехода.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Выполнено многоцентровое ретроспективное наблюдательное когортное исследование. Данные получены из медицинских карт 93 пациентов (38 мужчин, 55 женщин, средний возраст 39,9 ± 7,5 года), у которых выполнена тотальная артропластика межпозвонковых дисков на уровне пояснично-крестцового перехода. Оценивались как клинические параметры, так и результаты инструментальных исследований. Средняя длительность послеоперационного наблюдения составила 33,4 ± 9,5 мес.</p></sec><sec><title>Результаты</title><p>Результаты. Выраженность болевого синдрома в поясничном отделе позвоночного столба статистически значимо уменьшилась с 7,3 ± 2,5 до 1,9 ± 2,2 см по визуально-аналоговой шкале (р &lt;0,001). Индекс Освестри (Oswestry Disability Index) статистически значимо снизился с 43,4 ± 17,6 до 18,9 ± 16,0 % (р &lt;0,001), а качество жизни по шкале SF-36 (Short Form-36), включая ментальный и физический компоненты, повысилось c 30,8 ± 8,5 % до 52,3 ± 12,4 % (р &lt;0,001). Через 12 мес после операции амплитуда движений в оперированном позвоночно-двигательном сегменте статистически значимо уменьшилась с 5,3 ± 3,2° до 4,1 ± 3,6° (р &lt;0,009), амплитуда движений в смежном позвоночно-двигательном сегменте изменилась незначимо - с 8,6 ± 4,1° до 7,8 ± 3,8° (р &gt;0,05). Общий угол поясничного лордоза после установки протеза межпозвонкового диска на уровне пояснично-крестцового перехода статистически значимо увеличился с 49,1 ± 4,8° до 55,6 ± 5,5° (р &lt;0,001). Протезы межпозвонковых дисков с углом лордоза 10° статистически значимо положительно коррелируют с увеличением значений сегментарного лордоза, в отличие от имплантатов с углом 6° (rS = 0,86, р = 0,04). Выраженность болевого синдрома в поясничном отделе позвоночника по визуально-аналоговой шкале статистически значимо отрицательно коррелировала с амплитудой движений в оперированном сегменте на поздних сроках послеоперационного наблюдения (24 и 36 мес, rS = -0,74, р = 0,015).</p></sec><sec><title>Заключение</title><p>Заключение. Методика тотальной артропластики поясничных межпозвонковых дисков - эффективный способ хирургического лечения пациентов с дегенеративным заболеванием позвоночника на уровне пояснично-крестцового перехода.</p></sec></abstract><trans-abstract xml:lang="en"><p>The study objective is to analyze long-term clinical and radiological outcomes in patients after performing total lumbar disc replacement at the level of the lumbosacral junction.</p><sec><title>Materials and methods</title><p>Materials and methods. A multicenter retrospective observational cohort study was performed. The study included medical records of patients who underwent total lumbar disc replacement at the level of the lumbosacral junction. Both clinical and instrumental parameters were assessed. According to the eligibility criteria, 93 patients were included in the study (38 men, 55 women, mean age 39.9 ± 7.5 years). The average postoperative observation period for the respondents was 33.4 ± 9.5 months.</p></sec><sec><title>Results</title><p>Results. The severity of pain in the lumbar spine on a visual analogue scale significantly decreased (from 7.3 ± 2.5 to 1.9 ± 2.2 cm, p &lt;0.001). The indicators of the quality of life according to the Oswestry Disability Index and according to the Short Form-36 scale (including the mental and physical components) of the studied group of respondents significantly improved (from 43.4 ± 17.6 to 18.9 ± 16.0 %, р &lt;0.001 and from 30.8 ± 8.5 to 52.3 ± 12.4 %, p &lt;0.001, respectively). From the 12th month of observation of the respondents, a significant decrease in the values of the range of motions of the operated segment was noted from 5.3 ± 3.2° to 4.1 ± 3.6° (p &lt;0.009). Also, from the 12th month of postoperative observation, a slight decrease in the values of the range of motions of the adjacent segment from 8.6 ± 4.1° to 7.8 ± 3.8° (p &gt;0.05) was verified. The value of global lumbar lordosis after the installation of a lumbar intervertebral disc prosthesis at the level of the lumbosacral junction significantly increased from 49.1 ± 4.8° to 55.6 ± 5.5° (p &lt;0.001). Intervertebral disc prostheses with a lordotic angle of 10° reliably positively correlate with an increase in the values of segmental lordosis, in contrast to implants with an angle of 6° (rS = 0.86, p = 0.04). The severity of pain in the lumbar spine according to visual analogue scale and the range of motion of the operated segment has a significant negative correlation in the late periods of postoperative follow-up (24 and 36 months, rS = -0.74, p = 0.015).</p></sec><sec><title>Conclusion</title><p>Conclusion. The total lumbar disc replacement technique is an effective method of surgical treatment of patients with degenerative diseases of the intervertebral discs of the lumbosacral spine, including at the level of the lumbosacral junction.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>пояснично-крестцовый переход</kwd><kwd>межпозвонковый диск</kwd><kwd>дегенеративное заболевание</kwd><kwd>тотальная артропластика</kwd><kwd>отдаленные результаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lumbosacral junction</kwd><kwd>intervertebral disc</kwd><kwd>degenerative disease</kwd><kwd>total disc replacement</kwd><kwd>long-term outcomes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Коновалов Н.А., Назаренко А.Г., Асю-тин Д.С. и др. Современные методы лечения дегенеративных заболеваний межпозвонкового диска. Обзор литературы. Журнал «Вопросы нейрохирургии» им. Н.Н. 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